VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection (Q24302846)

vascular endothelial growth factor A

Europe PubMed Central

title

VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection (English)

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main subject

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nervous system development

GOA release 2020-03-11

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Improvement in chronic ischemic neuropathy after intramuscular phVEGF165 gene transfer in patients with critical limb ischemia

GOA release 2020-03-11

author

Diether Lambrechts

series ordinal

2

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Peter Carmeliet

series ordinal

3

object named as

Peter Carmeliet

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Erik Storkebaum

series ordinal

1

object named as

Erik Storkebaum

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language of work or name

English

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publication date

September 2004

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published in

BioEssays

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volume

26

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issue

9

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page(s)

943-54

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cites work

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Role of vascular endothelial growth factor in neuronal DNA damage and repair in rat brain following a transient cerebral ischemia

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Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis

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Absence of mutations in the hypoxia response element of VEGF in ALS

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Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR

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Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume

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Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

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Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).

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Focal reductions of cerebral blood flow in amyotrophic lateral sclerosis: a [99mTc]-d,l-HMPAO SPECT study

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Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia

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Behavioural and anatomical effects of systemically administered leukemia inhibitory factor in the SOD1(G93A G1H) mouse model of familial amyotrophic lateral sclerosis

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Immunohistochemical nitrotyrosine distribution in neonatal rat cerebrocortical slices during and after hypoxia

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Vascular endothelial growth factor stimulates Schwann cell invasion and neovascularization of acellular nerve grafts

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Inhibition of endogenous VEGF impedes revascularization and astroglial proliferation: roles for VEGF in brain repair

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Angiogenic and neurotrophic effects of vascular endothelial growth factor (VEGF165): studies of grafted and cultured embryonic ventral mesencephalic cells

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The vascular endothelial growth factor mRNA contains an internal ribosome entry site.

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Local cerebral blood flow in motor neuron disease: correlation with clinical findings

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

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Developmental control of blood cell migration by the Drosophila VEGF pathway

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Neurodegeneration: a failure of neuroregeneration?

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Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells

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VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death

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Vascular endothelial growth factor in Alzheimer's disease and experimental cerebral ischemia

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Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia

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7 January 2021

Caenorhabditis elegans receptors related to mammalian vascular endothelial growth factor receptors are expressed in neural cells

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7 January 2021

Expression of vascular endothelial growth factor and its receptors in rat neural stem cells.

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7 January 2021

Vascular endothelial growth factor expression in peripheral nerves and dorsal root ganglia in diabetic neuropathy in rats

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7 January 2021

Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor

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7 January 2021

Angiogenic and astroglial responses to vascular endothelial growth factor administration in adult rat brain

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7 January 2021

Vascular endothelial growth factor inhibits outward delayed-rectifier potassium currents in acutely isolated hippocampal neurons

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Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury

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7 January 2021

Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures

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7 January 2021

Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration

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The effect of leukaemia inhibitory factor on SOD1 G93A murine amyotrophic lateral sclerosis

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The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis

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7 January 2021

The role of the 5' untranslated region of an mRNA in translation regulation during development

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7 January 2021

VEGF165 therapy exacerbates secondary damage following spinal cord injury

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7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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7 January 2021

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

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7 January 2021

Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy

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7 January 2021

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

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7 January 2021

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

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7 January 2021

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

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7 January 2021

Angiogenesis in health and disease

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Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

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7 January 2021

Regeneration beyond the glial scar

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Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk-1 receptor

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7 January 2021

Expression of angiogenic factors in rabbit spinal cord after transient ischaemia

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7 January 2021

Induction of VEGF and VEGF receptors in the spinal cord after mechanical spinal injury and prostaglandin administration

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7 January 2021

A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor

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7 January 2021

VEGF enhances intraneural angiogenesis and improves nerve regeneration after axotomy

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7 January 2021

Enhancement of ischemia-induced tyrosine phosphorylation of Kv1.2 by vascular endothelial growth factor via activation of phosphatidylinositol 3-kinase.

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7 January 2021

Amyotrophic lateral sclerosis

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7 January 2021

Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

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7 January 2021

Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia

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7 January 2021

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia

1 reference

https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR

1 reference

https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis

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7 January 2021

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

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7 January 2021

VEGF is a chemoattractant for FGF-2-stimulated neural progenitors

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7 January 2021

Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy

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7 January 2021

Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability

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7 January 2021

Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling

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7 January 2021

Vascular endothelial growth factor (VEGF) and its receptors

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia

1 reference

https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia

1 reference

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7 January 2021

Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Cell type specific upregulation of vascular endothelial growth factor in an MCA-occlusion model of cerebral infarct

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7 January 2021

Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo

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7 January 2021

VEGF is necessary for exercise-induced adult hippocampal neurogenesis

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7 January 2021

Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease

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7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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7 January 2021

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

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7 January 2021

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

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7 January 2021

Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA

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7 January 2021

Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

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7 January 2021

Effect of age on cerebral blood flow: measurement with ungated two-dimensional phase-contrast MR angiography in 250 adults

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7 January 2021

Role of vascular endothelial growth factor in regulation of physiological angiogenesis

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7 January 2021

Small vessel disease and Alzheimer's dementia: pathological considerations

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7 January 2021

Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer

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7 January 2021

Rapid induction of vascular endothelial growth factor gene expression after transient middle cerebral artery occlusion in rats

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Spinal cord ischemia. Development of a model in the mouse

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Reversal of experimental diabetic neuropathy by VEGF gene transfer

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7 January 2021

Can VEGF reverse diabetic neuropathy in human subjects?

1 reference

https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain

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7 January 2021

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group

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7 January 2021

A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group

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7 January 2021

Macrophage-mediated corpse engulfment is required for normal Drosophila CNS morphogenesis.

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7 January 2021

Vascular endothelial growth factor rescues HN33 neural cells from death induced by serum withdrawal

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7 January 2021

Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system

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7 January 2021

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

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7 January 2021

Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.

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7 January 2021

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.

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https://api.crossref.org/works/10.1002%2FBIES.20092

7 January 2021

Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations

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7 January 2021

Promotion of regeneration of corticospinal tract axons in rats with recombinant vascular endothelial growth factor alone and combined with adenovirus coding for this factor.

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7 January 2021

Identifiers

DOI

10.1002/BIES.20092

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

15351965

1 reference

Consolidated OpenCitations Corpus – April 2017