The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT (Q24314421)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1990711

Catenin beta interacting protein 1

1 reference

The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

GOA release 2020-03-11

Wilson K Clements

2

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Wenqing Xu

object named as

Wenqing Xu

series ordinal

4

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author name string

Thomas A Graham

series ordinal

1

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David Kimelman

series ordinal

3

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language of work or name

English

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publication date

September 2002

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published in

Molecular Cell

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volume

10

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issue

3

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page(s)

563-71

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cites work

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ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

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Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway

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Adhesion signaling: how beta-catenin interacts with its partners

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Crystal structure of a beta-catenin/Tcf complex

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Tcf4 can specifically recognize beta-catenin using alternative conformations

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Signal transduction in development: holding the key.

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Identification of c-MYC as a target of the APC pathway

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Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression

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Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro

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The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

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The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

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Lessons from hereditary colorectal cancer

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Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

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Regulation of Lef-mediated transcription and p53-dependent pathway by associating beta-catenin with CBP/p300.

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beta-catenin signaling and cancer

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Molecular architecture of adherens junctions

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Structure of a human Tcf4-beta-catenin complex

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Association of the APC gene product with beta-catenin

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Wnt signalling: a theme with nuclear variations

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7 January 2021

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

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Regulation of beta -catenin transformation by the p300 transcriptional coactivator.

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The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression

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Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

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