Parkin is recruited selectively to impaired mitochondria and promotes their autophagy (Q24317471)

describes a project that uses

GOA release 2020-03-11

1 reference

4

Richard J Youle

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author name string

Derek Narendra

series ordinal

1

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Atsushi Tanaka

series ordinal

2

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Der-Fen Suen

series ordinal

3

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language of work or name

English

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publication date

1 December 2008

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number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

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volume

183

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issue

5

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page(s)

795-803

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ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2592826/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

1 reference

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The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division

19 March 2017

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Selective degradation of mitochondria by mitophagy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

19 March 2017

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19 March 2017

1 reference

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

19 March 2017

1 reference

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

19 March 2017

1 reference

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

19 March 2017

1 reference

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The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

7 April 2017

1 reference

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Essential role for Nix in autophagic maturation of erythroid cells

7 April 2017

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The PINK1/Parkin pathway regulates mitochondrial morphology

7 April 2017

1 reference

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NIX is required for programmed mitochondrial clearance during reticulocyte maturation

7 April 2017

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

7 April 2017

1 reference

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Disruption of fusion results in mitochondrial heterogeneity and dysfunction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

7 April 2017

1 reference

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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

7 April 2017

1 reference

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Genetics of Parkinson's disease and parkinsonism

27 September 2017

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The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Parkin enhances mitochondrial biogenesis in proliferating cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Disruption of mitochondrial networks by the human cytomegalovirus UL37 gene product viral mitochondrion-localized inhibitor of apoptosis

27 September 2017

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Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease?

27 September 2017

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Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Mitochondrial fusion intermediates revealed in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Complex I is the major site of mitochondrial superoxide production by paraquat

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Alterations in the common fragile site gene Parkin in ovarian and other cancers

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

The mitochondrial permeability transition initiates autophagy in rat hepatocytes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592826

29 November 2018

Identifiers

DOI

10.1083/JCB.200809125

1 reference

1 reference

1 reference

PubMed publication ID

19029340

1 reference