APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function (Q24318702)

GOA release 2020-03-11

author name string

Xuming Mao

1

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Chintan K Kikani

2

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Ramon A Riojas

3

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Paul Langlais

4

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Lixin Wang

5

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Fresnida J Ramos

6

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Qichen Fang

7

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Christine Y Christ-Roberts

8

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Jenny Y Hong

9

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Ryang-Yeo Kim

10

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Feng Liu

11

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Lily Q Dong

ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism

12

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language of work or name

English

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publication date

May 2006

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published in

Nature Cell Biology

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volume

8

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issue

5

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page(s)

516-23

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cites work

1 reference

7 January 2021

Adiponectin and adiponectin receptors

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ACRP30, a new hormone controlling fat and glucose metabolism

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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

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Disruption of adiponectin causes insulin resistance and neointimal formation

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Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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AdipoQ is a novel adipose-specific gene dysregulated in obesity

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Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

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Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes

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Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

1 reference

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A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1

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Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2

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7 January 2021

Mediation of the DCC apoptotic signal by DIP13 alpha

1 reference

7 January 2021

Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: potential involvement of the PI3K pathway in FSH signaling

1 reference

7 January 2021

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

1 reference

7 January 2021

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

7 January 2021

Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells.

1 reference

7 January 2021

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment

1 reference

7 January 2021

Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein

1 reference

7 January 2021

Regulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase

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Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton

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Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes.

1 reference

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Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10.

1 reference

7 January 2021

A family of Acrp30/adiponectin structural and functional paralogs

1 reference

7 January 2021

ConPred II: a consensus prediction method for obtaining transmembrane topology models with high reliability.

1 reference

7 January 2021