Human mediator subunit MED26 functions as a docking site for transcription elongation factors (Q24310867)

11

0 references

Ali Shilatifard

15

0 references

Joan W. Conaway

Joan W Conaway

17

0 references

Michael P. Washburn

Michael P Washburn

10

0 references

Chieri Tomomori-Sato

Chieri Tomomori-Sato

4

0 references

Selene K Swanson

8

Selene K Swanson

0 references

Ronald C Conaway

16

Ronald C Conaway

0 references

Shigeo Sato

3

Shigeo Sato

0 references

Tari J Parmely

2

Tari J Parmely

0 references

Skylar A Martin-Brown

9

Skylar Martin-Brown

0 references

Chris Seidel

12

Chris W Seidel

0 references

Chengqi Lin

13

Chengqi Lin

0 references

Hidehisa Takahashi

1

Hidehisa Takahashi

0 references

author name string

Charles A S Banks

5

0 references

Stephanie E Kong

6

0 references

Henrietta Szutorisz

7

0 references

Edwin R Smith

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

14

0 references

language of work or name

English

0 references

publication date

8 July 2011

0 references

published in

Cell

0 references

volume

146

0 references

issue

1

0 references

page(s)

92-104

0 references

cites work

1 reference

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c-Myc regulates transcriptional pause release

19 March 2017

1 reference

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A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription

19 March 2017

1 reference

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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

19 March 2017

1 reference

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ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL

19 March 2017

1 reference

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A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology

19 March 2017

1 reference

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TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA

19 March 2017

1 reference

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Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation

19 March 2017

1 reference

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Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

19 March 2017

1 reference

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The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1

19 March 2017

1 reference

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DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

19 March 2017

1 reference

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An RNA polymerase II elongation factor encoded by the human ELL gene

19 March 2017

1 reference

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Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70

19 March 2017

1 reference

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Mediator head module structure and functional interactions

19 March 2017

1 reference

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Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.

19 March 2017

1 reference

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A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

The human Mediator complex: a versatile, genome-wide regulator of transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Misguided transcriptional elongation causes mixed lineage leukemia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

CDK8 is a stimulus-specific positive coregulator of p53 target genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Controlling the elongation phase of transcription with P-TEFb

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Ras induces mediator complex exchange on C/EBP beta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Structure, function, and activator-induced conformations of the CRSP coactivator

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Promoter-associated pausing in promoter architecture and postinitiation transcriptional regulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Structure and function of RNA polymerase II elongation factor ELL. Identification of two overlapping ELL functional domains that govern its interaction with polymerase and the ternary elongation complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

A chromatin landmark and transcription initiation at most promoters in human cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Progression through the RNA polymerase II CTD cycle

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

RNA polymerase is poised for activation across the genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

An RNA polymerase II holoenzyme responsive to activators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

CDK8 is a positive regulator of transcriptional elongation within the serum response network

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Complexity in transcription control at the activation domain-mediator interface

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Regulation of the transcriptional activity of poised RNA polymerase II by the elongation factor ELL

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Transcription regulation through promoter-proximal pausing of RNA polymerase II.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

YY1 functions with INO80 to activate transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Breaking barriers to transcription elongation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Mediator requirement for both recruitment and postrecruitment steps in transcription initiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Transcription Factor and Polymerase Recruitment, Modification, and Movement on dhsp70 In Vivo in the Minutes following Heat Shock

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

P-TEFb kinase recruitment and function at heat shock loci

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Refinements to label free proteome quantitation: how to deal with peptides shared by multiple proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145325

Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21729782

12 December 2020

inferred from PubMed ID database lookup

MS1, MS2, and SQT-three unified, compact, and easily parsed file formats for the storage of shotgun proteomic spectra and identifications.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Analyzing chromatin remodeling complexes using shotgun proteomics and normalized spectral abundance factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Statistical Analysis of Membrane Proteome Expression Changes inSaccharomycescerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Proteomic Analysis by Multidimensional Protein Identification Technology

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.005

7 January 2021

10.1016/J.CELL.2011.06.005

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

21729782

1 reference