Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress (Q24320119)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress	scientific article

Statements

scholarly article

0 references

Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress (English)

0 references

1 reference

based on heuristic

inferred from title

solute carrier family 6 member 3

1 reference

GOA release 2020-03-11

Synuclein alpha

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Christophe Wersinger

1

0 references

Delphine Prou

2

0 references

Philippe Vernier

3

0 references

Anita Sidhu

4

0 references

language of work or name

0 references

publication date

November 2003

0 references

0 references

17

0 references

14

0 references

2151-3

0 references

Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Synphilin-1 is present in Lewy bodies in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-dependent differential regulation of genes encoding APP and alpha-synuclein in hippocampal synaptic plasticity

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunocytochemical localization of the dopamine transporter in human brain

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Review: formation and properties of amyloid-like fibrils derived from alpha-synuclein and related proteins

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Alpha-synuclein and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical comparison of alpha- and beta-synuclein in adult rat central nervous system

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure and function of the dopamine transporter

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple-system atrophy: a new alpha-synuclein disease?

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic and acute regulation of Na+/Cl- -dependent neurotransmitter transporters: drugs, substrates, presynaptic receptors, and signaling systems

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein-protein interactions of alpha-synuclein in brain homogenates and transfected cells

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Abnormal patterns of microtubule-associated protein-2 (MAP-2) immunolabeling in neuronal nuclei and Lewy bodies in Parkinson's disease substantia nigra brain tissues

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of cell death by alpha-synuclein is stimulus-dependent in mammalian cells

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Attenuation of dopamine transporter activity by alpha-synuclein

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential cytotoxicity of dopamine and H2O2 in a human neuroblastoma divided cell line transfected with α-synuclein and its familial Parkinson's disease-linked mutants

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Synuclein expression is decreased in rat substantia nigra following induction of apoptosis by intrastriatal 6-hydroxydopamine.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Filamentous nerve cell inclusions in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the lipid-binding domain of α-synuclein confer overlapping, yet distinct, functional properties in the regulation of dopamine transporter activity

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Lewy body diseases and multiple system atrophy as alpha-synucleinopathies

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple coupling of human D5 dopamine receptors to guanine nucleotide binding proteins Gs and Gz

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of alpha-synuclein and synphilin-1: effect of Parkinson's disease-associated mutations

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Tubulin seeds alpha-synuclein fibril formation

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Alpha-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

The synuclein family

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiology and pathophysiology of alpha-synuclein. Cell culture and transgenic animal models based on a Parkinson's disease-associated protein.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquinone (coenzyme q10) and mitochondria in oxidative stress of parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Absence of mutations in the coding region of the alpha-synuclein gene in pathologically proven Parkinson's disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Recent advances in the genetics and pathogenesis of Parkinson disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for alpha-synuclein in the regulation of dopamine biosynthesis

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

The control of dopamine neuron development, function and survival: insights from transgenic mice and the relevance to human disease

1 reference

https://api.crossref.org/works/10.1096%2FFJ.03-0152FJE

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1096/FJ.03-0152FJE

0 references

PubMed publication ID

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q24320119&oldid=2033080467"