CD14 is a cell-activating receptor for bacterial peptidoglycan (Q24321720)

peptidoglycan immune receptor activity

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

D Gupta

1

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T N Kirkland

2

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S Viriyakosol

3

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R Dziarski

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

20 September 1996

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published in

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volume

271

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issue

38

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page(s)

23310-6

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cites work

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Biochemistry of endotoxins

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Isolation of peptidoglycan and soluble peptidoglycan fragments

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The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure

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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

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Recognition of endotoxin by cells leading to transmembrane signaling

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Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

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A region of human CD14 required for lipopolysaccharide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.38.23310

Soluble CD14 truncated at amino acid 152 binds lipopolysaccharide (LPS) and enables cellular response to LPS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.38.23310

Lipopolysaccharide (LPS) signal transduction and clearance. Dual roles for LPS binding protein and membrane CD14.

21 January 2018

1 reference

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Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein

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Function and activation of NF-kappa B in the immune system

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Regulation of NF-?B activity in murine macrophages: Effect of bacterial lipopolysaccharide and phorbol ester

21 January 2018

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Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

21 January 2018

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Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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CD14 is a pattern recognition receptor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.38.23310

Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.38.23310

Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.38.23310

1.3E2, a variant of the B lymphoma 70Z/3, defective in activation of NF-?B and OTF-2

21 January 2018

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NF-kappa B: a lesson in family values

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7 January 2021

Differential activation of extracellular signal-regulated kinase (ERK) 1, ERK2, p38, and c-Jun NH2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan

1 reference

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7 January 2021

Evidence for the secretion of soluble peptidoglycans by clinical isolates of Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.38.23310

7 January 2021

The N-terminal half of membrane CD14 is a functional cellular lipopolysaccharide receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.38.23310

7 January 2021