Cleavage of membrane-bound CD40 ligand is not required for inducing B cell proliferation and differentiation (Q24323905)

GOA release 2020-03-11

CD40 ligand

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GOA release 2020-03-11

B cell proliferation

1 reference

GOA release 2020-03-11

author name string

F Pietravalle

1

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S Lecoanet-Henchoz

2

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J P Aubry

3

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G Elson

4

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J Y Bonnefoy

5

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J F Gauchat

European Journal of Immunology

6

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language of work or name

English

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publication date

March 1996

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published in

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volume

26

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issue

3

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page(s)

725-8

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cites work

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

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Molecular and biological characterization of a murine ligand for CD40

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Induction of human IgE synthesis in B cells by mast cells and basophils

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CD40 ligand is functionally expressed on human eosinophils

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Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

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CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

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Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM

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The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

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B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells

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Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen

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Mechanism of antigen-driven selection in germinal centres

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Generation of memory B cells and plasma cells in vitro.

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A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation

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A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF

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Expression of the functional soluble form of human fas ligand in activated lymphocytes.

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Human CD40‐ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production

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SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat

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“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

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Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help)

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Inhibition of human interleukin 4-induced IgE synthesis by a subset of anti-CD23/Fc epsilon RII monoclonal antibodies

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Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor

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CD40 ligand is a T cell growth factor

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