Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity (Q24336776)

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29 July 2024

author name string

J. K. Naggert

1

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L. D. Fricker

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O. Varlamov

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P. M. Nishina

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D. F. Steiner

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R. J. Carroll

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B. J. Paigen

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E. H. Leiter

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full work available at URL

29 July 2024

language of work or name

English

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publication date

June 1995

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http://www.nature.com/articles/ng0695-135

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http://www.nature.com/articles/ng0695-135.pdf

29 July 2024

file format

Portable Document Format

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Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

29 July 2024

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10

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issue

2

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page(s)

135-42

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cites work

1 reference

Positional cloning of the mouse obese gene and its human homologue

20 April 2017

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Direct identification of prohormone conversion site in insulin-secreting cells

20 April 2017

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A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus

20 April 2017

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The insulin-secretory-granule carboxypeptidase H. Purification and demonstration of involvement in proinsulin processing

20 April 2017

1 reference

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Human carboxypeptidase E. Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro

21 January 2018

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Primary structure and tissue distribution of anglerfish carboxypeptidase H

21 January 2018

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Insulin biosynthesis in experimental hereditary diabetes

21 January 2018

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pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle

21 January 2018

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Obesity genes and diabetes induction in the mouse

21 January 2018

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7 January 2021

Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage

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7 January 2021

Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse

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7 January 2021

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

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7 January 2021

Obesity-induced diabetes (diabesity) in C57BL/KsJ mice produces aberrant trans-regulation of sex steroid sulfotransferase genes

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7 January 2021

Synergism of obesity genes with hepatic steroid sulfotransferases to mediate diabetes in mice

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7 January 2021

A genetic map of the mouse with 4,006 simple sequence length polymorphisms

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7 January 2021

What beta-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism

1 reference

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7 January 2021

Isolation and sequence analysis of cDNA for rat carboxypeptidase E [EC 3.4.17.10], a neuropeptide processing enzyme

1 reference

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7 January 2021

Cloning and sequence analysis of cDNA for bovine carboxypeptidase E.

1 reference

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7 January 2021

Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships

1 reference

https://api.crossref.org/works/10.1038%2FNG0695-135

7 January 2021

Proinsulin as a marker for the development of NIDDM in Japanese-American men.

1 reference

https://api.crossref.org/works/10.1038%2FNG0695-135

7 January 2021

Hyperproinsulinemia and amyloid in NIDDM. Clues to etiology of islet beta-cell dysfunction?

1 reference

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7 January 2021

Banting lecture 1990. Beta-cells in type II diabetes mellitus

1 reference

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7 January 2021

Lessons learned from molecular biology of insulin-gene mutations

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7 January 2021

Hyperproinsulinemia of type II diabetes is not present before the development of hyperglycemia.

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7 January 2021

Hyperproinsulinemia and insulin deficiency in the diabetic Psammomys obesus.

1 reference

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7 January 2021

Immunoreactive C-peptide in spontaneous syndromes of obesity and diabetes in mice

1 reference

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7 January 2021

Structural Characterization of the Rat Carboxypeptidase-E Gene

1 reference

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7 January 2021

A mutation in adenylosuccinate lyase associated with mental retardation and autistic features

1 reference

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7 January 2021

NOR/Lt Mice: MHC-Matched Diabetes-Resistant Control Strain for NOD Mice

1 reference

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7 January 2021

MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations

1 reference

https://api.crossref.org/works/10.1038%2FNG0695-135

7 January 2021

Locus nomenclature updates by email

1 reference

https://api.crossref.org/works/10.1038%2FNG0695-135

7 January 2021

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BJ Paigen

1990

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