BOK and NOXA are essential mediators of p53-dependent apoptosis (Q24337595)

BCL2 associated X, apoptosis regulator

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Phorbol-12-myristate-13-acetate-induced protein 1

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intrinsic apoptotic signaling pathway by p53 class mediator

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author name string

Alexander G Yakovlev

1

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Simone Di Giovanni

2

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Geping Wang

3

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Wenfan Liu

4

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Bogdan Stoica

5

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Alan I Faden

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

2 July 2004

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published in

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volume

279

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issue

27

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page(s)

28367-74

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cites work

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Caspases induce cytochrome c release from mitochondria by activating cytosolic factors

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Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

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p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

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The Bcl2 family: regulators of the cellular life-or-death switch

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

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BH3-Only proteins-essential initiators of apoptotic cell death

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Molecular cloning and functional analysis of the murine bax gene promoter

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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PUMA induces the rapid apoptosis of colorectal cancer cells

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Quantitation of gene expression in neural precursors by reverse-transcription polymerase chain reaction using self-quenched, fluorogenic primers

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Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

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The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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Suppression of human colorectal carcinoma cell growth by wild-type p53

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The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death

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Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

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Nerve growth factor and epidermal growth factor rescue PC12 cells from programmed cell death induced by etoposide: distinct modes of protection against cell death by growth factors and a protein-synthesis inhibitor

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The apoptosome: heart and soul of the cell death machine

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

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Resistance of MCF7 human breast carcinoma cells to TNF-induced cell death is associated with loss of p53 function

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

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Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members

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The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

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Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis

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7 January 2021

Changes in nuclear chromatin precede internucleosomal DNA cleavage in the induction of apoptosis by etoposide

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7 January 2021

p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation

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7 January 2021

Mechanisms of p53-dependent apoptosis

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7 January 2021

The Role of CED-3-Related Cysteine Proteases in Apoptosis of Cerebellar Granule Cells

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Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury

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7 January 2021