Dopamine covalently modifies and functionally inactivates parkin (Q24338423)

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8 January 2020

title

Dopamine covalently modifies and functionally inactivates parkin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16227987%20AND%20SRC:MED&resulttype=core&format=json

ubiquitin protein ligase activity

8 January 2020

main subject

dopamine

0 references

1 reference

GOA release 2020-03-11

author name string

Matthew J LaVoie

series ordinal

1

1 reference

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8 January 2020

Beth L Ostaszewski

series ordinal

2

1 reference

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8 January 2020

Andreas Weihofen

series ordinal

3

1 reference

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8 January 2020

language of work or name

English

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publication date

16 October 2005

1 reference

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8 January 2020

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8 January 2020

volume

11

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8 January 2020

issue

11

1 reference

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8 January 2020

page(s)

1214-1221

1 reference

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

8 January 2020

cites work

1 reference

Lewy bodies and parkinsonism in families with parkin mutations

20 April 2017

1 reference

Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1

20 April 2017

1 reference

Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7

20 April 2017

1 reference

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

20 April 2017

1 reference

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

20 April 2017

1 reference

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

20 April 2017

1 reference

The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily

20 April 2017

1 reference

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

20 April 2017

1 reference

Molecular Pathways of Neurodegeneration in Parkinson's Disease

20 April 2017

1 reference

Parkinson's disease: mechanisms and models

20 April 2017

1 reference

Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers

21 January 2018

1 reference

Cytotoxic and genotoxic potential of dopamine

21 January 2018

1 reference

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics

21 January 2018

1 reference

Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

21 January 2018

1 reference

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections

21 January 2018

1 reference

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

21 January 2018

1 reference

The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: evidence for enzymatic parkin function in humans

21 January 2018

1 reference

Complex relationship between Parkin mutations and Parkinson disease

21 January 2018

1 reference

Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones

21 January 2018

1 reference

Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.

21 January 2018

1 reference

Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis

21 January 2018

1 reference

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

21 January 2018

1 reference

Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.

21 January 2018

1 reference

RING finger 1 mutations in Parkin produce altered localization of the protein

21 January 2018

1 reference

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

21 January 2018

1 reference

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

1 reference

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

21 January 2018

1 reference

Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease

21 January 2018

1 reference

Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease

21 January 2018

1 reference

Altered proteasomal function in sporadic Parkinson's disease

21 January 2018

1 reference

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

21 January 2018

1 reference

Occurrence and distribution of 5-S-cysteinyl derivatives of dopamine, dopa and dopac in the brains of eight mammalian species

21 January 2018

1 reference

The neuromelanin of human substantia nigra: physiological and pathogenic aspects

21 January 2018

1 reference

Intraneuronal dopamine-quinone synthesis: A review

21 January 2018

1 reference

Pathogenic mutations inactivate parkin by distinct mechanisms.

21 January 2018

1 reference

An autopsy case of autosomal-recessive juvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene.

21 January 2018

1 reference

7 January 2021

Dopamine quinone formation and protein modification associated with the striatal neurotoxicity of methamphetamine: evidence against a role for extracellular dopamine.

1 reference

7 January 2021

Dopamine inactivates tryptophan hydroxylase and forms a redox-cycling quinoprotein: possible endogenous toxin to serotonin neurons

1 reference

7 January 2021

Inhibition of glutamate transport in synaptosomes by dopamine oxidation and reactive oxygen species.

1 reference

7 January 2021

Modification of dopamine transporter function: effect of reactive oxygen species and dopamine.

1 reference

7 January 2021

Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase

1 reference

7 January 2021

The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset parkinsonism

1 reference

7 January 2021

Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport

1 reference

7 January 2021

Detection of 5-S-cysteinyldopamine in human brain

1 reference

7 January 2021

Elevated 5-S-cysteinyldopamine/homovanillic acid ratio and reduced homovanillic acid in cerebrospinal fluid: possible markers for and potential insights into the pathoetiology of Parkinson's disease

1 reference

7 January 2021

Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1314

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16227987%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 January 2020

1021749595

0 references

Fatcat ID

release_ejpw63xnjvgmzfbc6sacmjuv3e

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ejpw63xnjvgmzfbc6sacmjuv3e

24 November 2022

mapped directly with Wikidata item

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017