Gli proteins and the control of spinal-cord patterning (Q24536036)

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

Europe PubMed Central

title

Gli proteins and the control of spinal-cord patterning (English)

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James Briscoe

2

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author name string

John Jacob

series ordinal

1

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language of work or name

English

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publication date

August 2003

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published in

EMBO Reports

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volume

4

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issue

8

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page(s)

761-5

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cites work

1 reference

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24 March 2017

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24 March 2017

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

24 March 2017

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Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

24 March 2017

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Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

24 March 2017

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A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

24 March 2017

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24 March 2017

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Pallister-Hall syndrome phenotype in mice mutant for Gli3

24 March 2017

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Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord

24 March 2017

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Gli1 can rescue the in vivo function of Gli2

24 March 2017

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24 March 2017

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Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

24 March 2017

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Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

24 March 2017

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Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

24 March 2017

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Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

24 March 2017

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Gli proteins encode context-dependent positive and negative functions: implications for development and disease

24 March 2017

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Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system

24 March 2017

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Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1

24 March 2017

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Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

24 March 2017

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A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

24 March 2017

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Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

24 March 2017

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Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice

24 March 2017

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Neuronal specification in the spinal cord: inductive signals and transcriptional codes

24 March 2017

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Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development

7 April 2017

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Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

27 September 2017

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Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites.

27 September 2017

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Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

27 September 2017

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The specification of dorsal cell fates in the vertebrate central nervous system

27 September 2017

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Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog

27 September 2017

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Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

27 September 2017

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An absolute requirement for Cubitus interruptus in Hedgehog signaling

27 September 2017

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Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326336

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326336

Catching a Gli-mpse of Hedgehog

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326336

Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326336

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.EMBOR896

Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.EMBOR896

Wnt signals are targets and mediators of Gli function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.EMBOR896

Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.EMBOR896

Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.EMBOR896

Nuclear import of cubitus interruptus is regulated by hedgehog via a mechanism distinct from Ci stabilization and Ci activation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326336

Bmp activity establishes a gradient of positional information throughout the entire neural plate

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1326336

Carboxy-terminally truncated Gli3 proteins associate with Smads

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12897799

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12897799

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.EMBOR896

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOR.EMBOR896

1 reference

1 reference

1 reference

PubMed publication ID

12897799

1 reference