Platelet genomics and proteomics in human health and disease (Q24536151)

5 July 2017

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title

Platelet genomics and proteomics in human health and disease (English)

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5 July 2017

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Iain C Macaulay

1

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Willem H. Ouwehand

4

object named as

Willem H Ouwehand

1 reference

5 July 2017

Philippa Carr

2

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5 July 2017

Arief Gusnanto

3

1 reference

5 July 2017

Des Fitzgerald

5

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5 July 2017

Nicholas A Watkins

6

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5 July 2017

language of work or name

English

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publication date

1 December 2005

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Journal of Clinical Investigation

5 July 2017

published in

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5 July 2017

volume

115

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5 July 2017

issue

12

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5 July 2017

page(s)

3370-3377

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Reactome: a knowledgebase of biological pathways

5 July 2017

cites work

1 reference

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24 March 2017

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Statistical tests for differential expression in cDNA microarray experiments

24 March 2017

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Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in platelets

24 March 2017

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Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets

24 March 2017

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Finishing the euchromatic sequence of the human genome

24 March 2017

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Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides

24 March 2017

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A gene-expression signature as a predictor of survival in breast cancer

24 March 2017

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Gene expression profiling predicts clinical outcome of breast cancer

24 March 2017

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24 March 2017

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Functional rafts in cell membranes

24 March 2017

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Serial analysis of gene expression

24 March 2017

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24 March 2017

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24 March 2017

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24 March 2017

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A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

24 March 2017

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High-throughput mapping of a dynamic signaling network in mammalian cells

24 March 2017

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Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins

24 March 2017

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Nomenclature of human platelet antigens

24 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Identification of the phosphotyrosine proteome from thrombin activated platelets

24 March 2017

1 reference

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Towards complete analysis of the platelet proteome

24 March 2017

1 reference

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Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

24 March 2017

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A map of the interactome network of the metazoan C. elegans

24 March 2017

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

7 April 2017

1 reference

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Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Global identification of human transcribed sequences with genome tiling arrays

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Direct analysis of protein complexes using mass spectrometry

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets

7 April 2017

1 reference

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The human platelet proteome mapped by peptide-centric proteomics: a functional protein profile

27 September 2017

1 reference

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Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation

27 September 2017

1 reference

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Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2.

27 September 2017

1 reference

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MADE4: an R package for multivariate analysis of gene expression data

27 September 2017

1 reference

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Using proteomics to identify potential therapeutic targets in platelets.

27 September 2017

1 reference

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Integrated transcriptome and proteome data: the challenges ahead

27 September 2017

1 reference

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Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.

27 September 2017

1 reference

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Platelets: signaling cells in the immune continuum.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Massively parallel signature sequencing (MPSS) as a tool for in-depth quantitative gene expression profiling in all organisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Gene expression profile of primary human CD34+CD38lo cells differentiating along the megakaryocyte lineage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Integration of proteomics and genomics in platelets: a profile of platelet proteins and platelet-specific genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Characterization of platelet-specific mRNA by real-time PCR after laser-assisted microdissection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Differential analysis of phosphorylated proteins in resting and thrombin-stimulated human platelets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Megakaryocytes and beyond: the birth of platelets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Options available--from start to finish--for obtaining data from DNA microarrays II.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Transcript profiling of human platelets using microarray and serial analysis of gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Identification of platelet proteins separated by two-dimensional gel electrophoresis and analyzed by matrix assisted laser desorption/ionization-time of flight-mass spectrometry and detection of tyrosine-phosphorylated proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Proteomics to study genes and genomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

The current state of two-dimensional electrophoresis with immobilized pH gradients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

A fast and convenient MALDI-MS based proteomic approach: identification of components scaffolded by the actin cytoskeleton of activated human thrombocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Biosynthesis of major platelet proteins in human blood platelets.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Enzymatic amplification of platelet-specific messenger RNA using the polymerase chain reaction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Platelet membrane glycoproteins implicated in ristocetin-induced aggregation. Studies of the proteins on platelets from patients with Bernard-Soulier syndrome and von Willebrand's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Dimorphism in the P2Y1 ADP receptor gene is associated with increased platelet activation response to ADP.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Gene expression analysis in platelets from a single donor: evaluation of a PCR-based amplification technique

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Transcriptional down-regulation of the platelet ADP receptor P2Y(12) and clusterin in patients with systemic lupus erythematosus

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Gene expression profiling of normal and malignant CD34-derived megakaryocytic cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Reversible labeling of cysteine-containing peptides allows their specific chromatographic isolation for non-gel proteome studies

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Extensive analysis of the human platelet proteome by two-dimensional gel electrophoresis and mass spectrometry

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Gene expression profiling in polycythemia vera using cDNA microarray technology.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Use of a cDNA microarray to determine molecular mechanisms involved in grey platelet syndrome.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Gene expression profile of megakaryocytes from human cord blood CD34(+) cells ex vivo expanded by thrombopoietin

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Proteomics and its trends facing nature's complexity.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297260

Participation of tyrosine phosphorylation in cytoskeletal reorganization, alpha(IIb)beta(3) integrin receptor activation, and aspirin-insensitive mechanisms of thrombin-stimulated human platelets

29 November 2018

1 reference

12 December 2020

Messenger RNA profiling of human platelets by microarray hybridization

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12 December 2020

Two-dimensional polyacrylamide gel electrophoresis for platelet proteomics

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12 December 2020

Studies on human platelets. I. Synthesis of platelet protein in a cell-free system

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12 December 2020

TFBScluster: a resource for the characterization of transcriptional regulatory networks

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12 December 2020

Isolation and characterization of human blood platelet mRNA and construction of a cDNA library in lambda gt11. Confirmation of the platelet derivation by identification of GPIb coding mRNA and cloning of a GPIb coding cDNA insert

1 reference

12 December 2020

Human blood platelet protein map established by two-dimensional polyacrylamide gel electrophoresis

1 reference

12 December 2020

Identification of phosphorylated proteins from thrombin-activated human platelets isolated by two-dimensional gel electrophoresis by electrospray ionization-tandem mass spectrometry (ESI-MS/MS) and liquid chromatography-electrospray ionization-mass

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI26885

1 reference

5 July 2017

1 reference

5 July 2017

1 reference