Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes (Q24551045)

1

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S M Medghalchi

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R G Lake

3

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E N Noensie

4

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H C Dietz

Molecular and Cellular Biology

5

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language of work or name

English

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publication date

December 2000

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published in

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volume

20

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issue

23

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page(s)

8944-57

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cites work

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Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation

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Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein

24 March 2017

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24 March 2017

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Mammalian orthologues of a yeast regulator of nonsense transcript stability

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24 March 2017

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Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p

24 March 2017

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A factor required for nonsense-mediated mRNA decay in yeast is exported from the nucleus to the cytoplasm by a nuclear export signal sequence.

24 March 2017

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Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay

24 March 2017

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Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover

24 March 2017

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Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen

24 March 2017

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The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm

24 March 2017

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Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

24 March 2017

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High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier

24 March 2017

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A tale of two termini: a functional interaction between the termini of an mRNA is a prerequisite for efficient translation initiation

24 March 2017

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Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1

24 March 2017

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A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme

24 March 2017

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Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

24 March 2017

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Nonsense-mediated mRNA decay in health and disease

7 April 2017

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Starting at the beginning, middle, and end: translation initiation in eukaryotes

7 April 2017

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Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G

7 April 2017

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Premature translational termination triggers mRNA decapping

7 April 2017

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The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon

7 April 2017

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Degradation of mRNA in eukaryotes

7 April 2017

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Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation: implications for the control of mRNA decapping

7 April 2017

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Yeast Upf proteins required for RNA surveillance affect global expression of the yeast transcriptome

27 September 2017

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Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover

27 September 2017

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Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae

27 September 2017

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Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay.

27 September 2017

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27 September 2017

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smg-7 is required for mRNA surveillance in Caenorhabditis elegans.

27 September 2017

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mRNA stabilization by poly(A) binding protein is independent of poly(A) and requires translation.

27 September 2017

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A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells

27 September 2017

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Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway

27 September 2017

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Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86549

Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86549

A single-base-pair deletion in the beta-glucuronidase gene accounts for the phenotype of murine mucopolysaccharidosis type VII

27 September 2017

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Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance

27 September 2017

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Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay

27 September 2017

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27 September 2017

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When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.

27 September 2017

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27 September 2017

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Nonsense mutations in the dihydrofolate reductase gene affect RNA processing

27 September 2017

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27 September 2017

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27 September 2017

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Gene products that promote mRNA turnover in Saccharomyces cerevisiae

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27 September 2017

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27 September 2017

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27 September 2017

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Thiamine-repressible expression vectors pREP and pRIP for fission yeast

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