Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin (Q24568252)

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English	Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin	scientific article

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25 October 2019

Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin (English)

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25 October 2019

Hans-Dieter Klenk

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Schäfer W

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25 October 2019

Stroh A

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Berghöfer S

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Seiler J

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Vey M

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Kruse ML

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Kern HF

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Garten W

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1 June 1995

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25 October 2019

The EMBO Journal

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25 October 2019

2424-2435

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25 October 2019

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

1 reference

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24 March 2017

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Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

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Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin

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TGN38 is maintained in the trans-Golgi network by a tyrosine-containing motif in the cytoplasmic domain

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Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence

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Oligomerization of a membrane protein correlates with its retention in the Golgi complex

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Sequence specificity of furin, a proprotein-processing endoprotease, for the hemagglutinin of a virulent avian influenza virus.

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Retrieval of TGN proteins from the cell surface requires endosomal acidification.

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Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2.

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27 September 2017

The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.

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Control of protein exit from the endoplasmic reticulum

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Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R

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30 May 2018

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30 May 2018

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30 May 2018

The trans-Golgi network can be dissected structurally and functionally from the cisternae of the Golgi complex by brefeldin A

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The internalization signal in the cytoplasmic tail of lysosomal acid phosphatase consists of the hexapeptide PGYRHV

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30 May 2018

Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398356

30 May 2018

Molecular and enzymatic properties of furin, a Kex2-like endoprotease involved in precursor cleavage at Arg-X-Lys/Arg-Arg sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398356

19 June 2018

Proteolytic processing of human cytomegalovirus glycoprotein B (gpUL55) is mediated by the human endoprotease furin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398356

28 November 2018

Protein sorting by selective retention in the endoplasmic reticulum and Golgi stack

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398356

28 November 2018

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/7781597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SXYQRL sequence in the cytoplasmic domain of TGN38 plays a major role in trans-Golgi network localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/7781597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective processing of the insulin receptor in an endoprotease-deficient Chinese hamster cell strain is corrected by expression of mouse furin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7781597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/7781597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1995.TB07240.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7781597%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7781597%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7781597%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

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