Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1 (Q24600785)

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10 November 2019

title

Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1 (English)

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10 November 2019

1 reference

1 reference

4

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10 November 2019

Kristian Helin

10

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10 November 2019

author name string

B O Petersen

1

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10 November 2019

C Wagener

2

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10 November 2019

F Marinoni

3

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10 November 2019

M Melixetian

5

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10 November 2019

E Lazzerini Denchi

6

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10 November 2019

C Gieffers

7

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10 November 2019

C Matteucci

8

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10 November 2019

J M Peters

9

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10 November 2019

language of work or name

English

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publication date

1 September 2000

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10 November 2019

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10 November 2019

volume

14

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10 November 2019

issue

18

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10 November 2019

page(s)

2330-2343

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The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

10 November 2019

cites work

1 reference

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Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity

7 April 2017

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Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons

7 April 2017

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Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

7 April 2017

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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

7 April 2017

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Cdc6 protein causes premature entry into S phase in a mammalian cell-free system

7 April 2017

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Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

7 April 2017

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Geminin, an inhibitor of DNA replication, is degraded during mitosis

7 April 2017

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Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

7 April 2017

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Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

7 April 2017

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The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

7 April 2017

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Induction of S-phase entry by E2F transcription factors depends on their nuclear localization

7 April 2017

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A human protein related to yeast Cdc6p

7 April 2017

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G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus

7 April 2017

1 reference

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Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

7 April 2017

1 reference

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Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs

7 April 2017

1 reference

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Cyclin is degraded by the ubiquitin pathway

7 April 2017

1 reference

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Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

7 April 2017

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Emerging mechanisms of eukaryotic DNA replication initiation

7 April 2017

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SCF and APC: the Yin and Yang of cell cycle regulated proteolysis

7 April 2017

1 reference

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Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family

7 April 2017

1 reference

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Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

7 April 2017

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The regulation of E2F by pRB-family proteins

7 April 2017

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Initiation of DNA replication in eukaryotic cells

7 April 2017

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The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts

7 April 2017

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ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

7 April 2017

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Mitotic regulation of the APC activator proteins CDC20 and CDH1

7 April 2017

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The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells

7 April 2017

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A short amino acid sequence able to specify nuclear location

7 April 2017

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Temporal and spatial control of cyclin B1 destruction in metaphase

7 April 2017

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Whose end is destruction: cell division and the anaphase-promoting complex

7 April 2017

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Proteasome inhibitors: valuable new tools for cell biologists

7 April 2017

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Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

7 April 2017

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Distinct roles for cyclin-dependent kinases in cell cycle control

7 April 2017

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Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

7 April 2017

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Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis

7 April 2017

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E2F activates late-G1 events but cannot replace E1A in inducing S phase in terminally differentiated skeletal muscle cells

27 September 2017

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The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin

27 September 2017

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Improved cervical smear assessment using antibodies against proteins that regulate DNA replication

27 September 2017

1 reference

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Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

27 September 2017

1 reference

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Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

27 September 2017

1 reference

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Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation

27 September 2017

1 reference

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Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.

27 September 2017

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Cell cycle control of DNA replication.

27 September 2017

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The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase

27 September 2017

1 reference

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Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast

27 September 2017

1 reference

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Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

27 September 2017

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Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

27 September 2017

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Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells

27 September 2017

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Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

27 September 2017

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Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders

30 May 2018

1 reference

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The fission yeast cdc18+ gene product couples S phase to START and mitosis

28 November 2018

1 reference

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Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis.

28 November 2018

1 reference

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In vivo ubiquitination and proteasome-mediated degradation of p53(1)

28 November 2018

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12 December 2020

A distinct G1 step required to specify the Chinese hamster DHFR replication origin

1 reference

12 December 2020

Functionally homologous DNA replication genes in fission and budding yeast

1 reference

12 December 2020

The spatial position and replication timing of chromosomal domains are both established in early G1 phase

1 reference

12 December 2020

CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis

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12 December 2020

A p53-dependent mouse spindle checkpoint

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12 December 2020

Identifiers

DOI

10.1101/GAD.832500

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995389%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995389%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

10995389

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995389%20AND%20SRC:MED&resulttype=core&format=json