Crystal structure of the β2 adrenergic receptor-Gs protein complex (Q24635327)

9

0 references

Joseph A Lyons

Joseph A Lyons

13

0 references

Martin Caffrey

Martin Caffrey

14

0 references

William I Weis

William I Weis

18

0 references

Jesper M Mathiesen

Jesper M Mathiesen

11

0 references

Georgios Skiniotis

17

Georgios Skiniotis

0 references

Brian Kobilka

20

Brian K Kobilka

0 references

Tong Sun Kobilka

6

Tong Sun Kobilka

0 references

Pil Seok Chae

8

Pil Seok Chae

0 references

Søren G. F. Rasmussen

1 reference

ORCID Public Data File 2021

Roger K Sunahara

19

Roger K Sunahara

0 references

Foon Sun Thian

7

Foon Sun Thian

0 references

Samuel H. Gellman

15

Samuel H Gellman

0 references

Yaozhong Zou

3

Yaozhong Zou

0 references

author name string

Søren G F Rasmussen

1

0 references

Brian T DeVree

2

0 references

Andrew C Kruse

4

0 references

Ka Young Chung

5

0 references

Diane Calinski

10

0 references

Syed T A Shah

Structure and function of an irreversible agonist-β(2) adrenoceptor complex

12

0 references

language of work or name

English

0 references

publication date

29 September 2011

0 references

published in

Nature

0 references

volume

477

0 references

issue

7366

0 references

page(s)

549-55

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

MolProbity: all-atom structure validation for macromolecular crystallography

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Crystal structure of metarhodopsin II

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

The structural basis of agonist-induced activation in constitutively active rhodopsin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic 2-microglobulin variant

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Structure of a beta1-adrenergic G-protein-coupled receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Crystal structure of the adenylyl cyclase activator Gsalpha

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Phasercrystallographic software

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Solving structures of protein complexes by molecular replacement with Phaser

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Coot: model-building tools for molecular graphics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Transduction of receptor signals by beta-arrestins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Super-resolution biomolecular crystallography with low-resolution data

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Crystallizing membrane proteins using lipidic mesophases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

G protein mechanisms: insights from structural analysis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

A robust bulk-solvent correction and anisotropic scaling procedure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit

26 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Complexes between photoactivated rhodopsin and transducin: progress and questions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

A G protein-coupled receptor at work: the rhodopsin model.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Heterotrimeric G protein activation by G-protein-coupled receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Receptor-mediated activation of heterotrimeric G-proteins: current structural insights.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Seven transmembrane receptors: something old, something new.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Membrane protein crystallization in lipidic mesophases with tailored bilayers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

G protein-coupled receptor oligomerization: implications for G protein activation and cell signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Relationship between the beta-adrenergic receptor and adenylate cyclase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Separate GTP binding and GTPase activating domains of a G alpha subunit

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Allosteric modulation of beta2-adrenergic receptor by Zn(2+).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184188

Processing of X-ray diffraction data collected in oscillation mode

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772288

12 December 2020

inferred from PubMed ID database lookup

Reconstitution of catecholamine-stimulated guanosinetriphosphatase activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772288

12 December 2020

inferred from PubMed ID database lookup

The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772288

12 December 2020

inferred from PubMed ID database lookup

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE10361

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE10361

1 reference

Dimensions Publication ID

1008768060

0 references

1 reference

1 reference

PubMed publication ID

21772288

1 reference