Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses (Q24631052)

Norihito Shibata

6

0 references

Christopher K Glass

Christopher K Glass

26

0 references

David W. Russell

David W Russell

25

0 references

Edward A. Dennis

Edward A Dennis

18

0 references

Eoin Fahy

22

Eoin Fahy

0 references

Sotirios Tsimikas

21

Sotirios Tsimikas

0 references

Daniel Heudobler

10

Daniel Heudobler

0 references

author name string

Nathanael J Spann

1

0 references

Lana X Garmire

2

0 references

Jeffrey G McDonald

3

0 references

David S Myers

4

0 references

Stephen B Milne

5

0 references

Donna Reichart

7

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Jesse N Fox

8

0 references

Iftach Shaked

9

0 references

Christian R H Raetz

11

0 references

Elaine W Wang

12

0 references

Samuel L Kelly

13

0 references

M Cameron Sullards

14

0 references

Alfred H Merrill

16

0 references

H Alex Brown

17

0 references

Andrew C Li

19

0 references

Klaus Ley

20

0 references

Shankar Subramaniam

23

0 references

Oswald Quehenberger

Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.

24

0 references

language of work or name

English

0 references

publication date

28 September 2012

0 references

published in

Cell

0 references

volume

151

0 references

issue

1

0 references

page(s)

138-52

0 references

cites work

1 reference

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7 April 2017

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LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

7 April 2017

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Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

7 April 2017

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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

7 April 2017

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Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein

7 April 2017

1 reference

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

7 April 2017

1 reference

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Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

7 April 2017

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C-reactive protein and other inflammatory risk markers in acute coronary syndromes

7 April 2017

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Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

7 April 2017

1 reference

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

7 April 2017

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Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

7 April 2017

1 reference

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The pathogenesis of atherosclerosis: a perspective for the 1990s

7 April 2017

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

7 April 2017

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Atherosclerosis. the road ahead

7 April 2017

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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

7 April 2017

1 reference

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Macrophage death and defective inflammation resolution in atherosclerosis

7 April 2017

1 reference

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Macrophage heterogeneity in atherosclerotic plaques

27 September 2017

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Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

27 September 2017

1 reference

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Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake

27 September 2017

1 reference

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Obesity, inflammation, and atherosclerosis

27 September 2017

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The LDL modification hypothesis of atherogenesis: an update

27 September 2017

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Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes

27 September 2017

1 reference

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Oxidation-specific epitopes are important targets of innate immunity

27 September 2017

1 reference

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Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

27 September 2017

1 reference

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Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

27 September 2017

1 reference

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Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.

27 September 2017

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Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns

27 September 2017

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Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.

27 September 2017

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Diet and murine atherosclerosis

27 September 2017

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Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma

27 September 2017

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Chemokines in the pathogenesis of vascular disease

27 September 2017

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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

27 September 2017

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Oxidized low density lipoprotein and innate immune receptors

27 September 2017

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27 September 2017

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Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases

27 September 2017

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27 September 2017

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The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis

27 September 2017

1 reference

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Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL.

30 May 2018

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Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis

30 May 2018

1 reference

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Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands.

28 November 2018

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Mechanism of action of MER-29, an inhibitor of cholesterol biosynthesis

28 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23021221

12 December 2020

inferred from PubMed ID database lookup

Inflammation and atherosclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23021221

12 December 2020

inferred from PubMed ID database lookup

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.06.054

7 January 2021

inferred from DOI database lookup

Statistical analysis of high-density oligonucleotide arrays: a multiplicative noise model.

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.06.054

7 January 2021

inferred from DOI database lookup

DAVID: Database for Annotation, Visualization, and Integrated Discovery

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.06.054

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.CELL.2012.06.054

1 reference

1 reference

1 reference

PubMed publication ID

23021221

1 reference