Statistical methods for analysis of high-throughput RNA interference screens (Q24644919)

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4 February 2020

review article

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title

Statistical methods for analysis of high-throughput RNA interference screens (English)

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4 February 2020

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3

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4 February 2020

Emma Shanks

6

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4 February 2020

Javier Santoyo-Lopez

7

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4 February 2020

Dara Dunican

8

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4 February 2020

Aideen Long

9

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4 February 2020

Peter Ghazal

13

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4 February 2020

author name string

Amanda Birmingham

1

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4 February 2020

Laura M Selfors

2

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4 February 2020

David Wrobel

4

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4 February 2020

Caleb J Kennedy

5

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4 February 2020

Dermot Kelleher

10

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4 February 2020

Queta Smith

11

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4 February 2020

Roderick L Beijersbergen

12

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4 February 2020

Caroline E Shamu

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4 February 2020

language of work or name

English

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publication date

1 August 2009

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4 February 2020

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4 February 2020

volume

6

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4 February 2020

issue

8

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4 February 2020

page(s)

569-575

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Characteristic differences between the promoters of intron-containing and intronless ribosomal protein genes in yeast

4 February 2020

cites work

1 reference

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Hit selection with false discovery rate control in genome-scale RNAi screens

7 April 2017

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Novel analytic criteria and effective plate designs for quality control in genome-scale RNAi screens

7 April 2017

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Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens

7 April 2017

1 reference

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A pair of new statistical parameters for quality control in RNA interference high-throughput screening assays

7 April 2017

1 reference

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

7 April 2017

1 reference

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An introduction to ROC analysis

7 April 2017

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https://api.crossref.org/works/10.1038/NMETH.1351

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

22 April 2017

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Expression profiling reveals off-target gene regulation by RNAi

7 April 2017

1 reference

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Determination of sample size in genome-scale RNAi screens

7 April 2017

1 reference

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RNAither, an automated pipeline for the statistical analysis of high-throughput RNAi screens

27 September 2017

1 reference

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An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme

27 September 2017

1 reference

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The art and design of genetic screens: RNA interference.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789971

Median absolute deviation to improve hit selection for genome-scale RNAi screens

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789971

Design and implementation of high-throughput RNAi screens in cultured Drosophila cells

27 September 2017

1 reference

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A new method with flexible and balanced control of false negatives and false positives for hit selection in RNA interference high-throughput screening assays

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789971

High-throughput screening by RNA interference: control of two distinct types of variance

27 September 2017

1 reference

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Synthetic lethal screen identification of chemosensitizer loci in cancer cells

27 September 2017

1 reference

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Applications of high-throughput RNA interference screens to problems in cell and developmental biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789971

Robust statistical methods for hit selection in RNA interference high-throughput screening experiments

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789971

From genome to phenome--RNAi library screening and hit characterization using signaling pathway analysis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789971

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

27 September 2017

1 reference

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Statistical practice in high-throughput screening data analysis

27 September 2017

1 reference

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Functional genomics reveals genes involved in protein secretion and Golgi organization

27 September 2017

1 reference

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Identification of JAK/STAT signalling components by genome-wide RNA interference.

27 September 2017

1 reference

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Functional genomic analysis of the Wnt-wingless signaling pathway

27 September 2017

1 reference

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Genomics, prior probability, and statistical tests of multiple hypotheses.

27 September 2017

1 reference

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Improved statistical methods for hit selection in high-throughput screening

27 September 2017

1 reference

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Statistical and graphical methods for quality control determination of high-throughput screening data

27 September 2017

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Experiments using microarray technology: limitations and standard operating procedures

27 September 2017

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Practical approaches to long oligonucleotide-based DNA microarray: lessons from herpesviruses

27 September 2017

1 reference

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Analysis of cell-based RNAi screens.

27 September 2017

1 reference

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Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

30 May 2018

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A probability-based approach for the analysis of large-scale RNAi screens.

30 May 2018

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The use of strictly standardized mean difference for hit selection in primary RNA interference high-throughput screening experiments

28 November 2018

1 reference

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Minimizing the risk of reporting false positives in large-scale RNAi screens

28 November 2018

1 reference

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Error rates and powers in genome-scale RNAi screens

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19644458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genome-wide screens for effective siRNAs through assessing the size of siRNA effects

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19644458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NMETH.1351

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19644458%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 February 2020

1046739948

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19644458%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

19644458

2 references