In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression (Q24650986)

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English	In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression	scientific article

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scholarly article

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In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression (English)

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author name string

S Tommasi

1

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G P Pfeifer

2

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language of work or name

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publication date

December 1995

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Molecular and Cellular Biology

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15

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12

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6901-13

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The retinoblastoma protein binds to a family of E2F transcription factors

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Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

1 reference

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7 April 2017

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

1 reference

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7 April 2017

E2F-5, a new E2F family member that interacts with p130 in vivo

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7 April 2017

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7 April 2017

Human DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cells

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7 April 2017

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

1 reference

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7 April 2017

Cyclin A is required at two points in the human cell cycle

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7 April 2017

The retinoblastoma protein and cell cycle control

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7 April 2017

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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7 April 2017

57 Sequencing end-labeled DNA with base-specific chemical cleavages

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7 April 2017

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

7 April 2017

A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase

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7 April 2017

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

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7 April 2017

E2F-4, a new member of the E2F transcription factor family, interacts with p107

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

7 April 2017

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

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7 April 2017

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

7 April 2017

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

7 April 2017

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

1 reference

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7 April 2017

Differential regulation of E2F transactivation by cyclin/cdk2 complexes

1 reference

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7 April 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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7 April 2017

G1 phase progression: cycling on cue

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7 April 2017

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

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7 April 2017

G1 events and regulation of cell proliferation

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7 April 2017

The E2F transcription factor is a cellular target for the RB protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

7 April 2017

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

7 April 2017

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

1 reference

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7 April 2017

A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter

1 reference

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28 September 2017

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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28 September 2017

The role of E2F in the mammalian cell cycle

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28 September 2017

In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response

1 reference

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28 September 2017

An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

DP and E2F proteins: components of a heterodimeric transcription factor implicated in cell cycle control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

pRB, p107 and the regulation of the E2F transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

G1 control in mammalian cells.

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28 September 2017

Periodic cdc25C transcription is mediated by a novel cell cycle-regulated repressor element (CDE).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

A complex between E2F and the pRb-related protein p130 is specifically targeted by the simian virus 40 large T antigen during cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

Identification of a cell-type-specific and E2F-independent mechanism for repression of cdc2 transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

A role for Y-box proteins in cell proliferation

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28 September 2017

A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable

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28 September 2017

Genomic sequencing and methylation analysis by ligation mediated PCR.

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28 September 2017

In vivo footprinting of a muscle specific enhancer by ligation mediated PCR.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

28 September 2017

Periodic biosynthesis of the human M-phase promoting factor catalytic subunit p34 during the cell cycle

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28 September 2017

Cyclins and cancer

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28 September 2017

Cyclin A and the retinoblastoma gene product complex with a common transcription factor

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28 September 2017

G1-specific cyclins: in search of an S-phase-promoting factor

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28 September 2017

A procedure to standardize CAT reporter gene assay

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28 September 2017

Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

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28 September 2017

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

1 reference

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28 September 2017

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28 September 2017

Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene

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28 September 2017

Coordinated synthesis and degradation of cdc2 in the mammalian cell cycle

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28 September 2017

CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle

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28 September 2017

Association of cdk2 Kinase with the Transcription Factor E2F During S Phase

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28 September 2017

Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex

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28 September 2017

c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

1 reference

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30 May 2018

Cell cycle-specific association of E2F with the p130 E1A-binding protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

c-Myc cooperates with activated Ras to induce the cdc2 promoter

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

ets-2 regulates cdc2 kinase activity in mammalian cells: coordinated expression of cdc2 and cyclin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

Mechanism of active transcriptional repression by the retinoblastoma protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1.

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30 May 2018

Cell cycle control of DNA replication by a homologue from human cells of the p34cdc2 protein kinase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.

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30 May 2018

Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

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30 May 2018

Transcriptional regulation. A closer look at E2F.

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30 May 2018

Cell cycle regulation of the human cdc2 gene

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230945

30 May 2018

Retinoblastoma protein switches the E2F site from positive to negative element

1 reference

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30 May 2018

Effect of tumor suppressors on cell cycle-regulatory genes: RB suppresses p34cdc2 expression and normal p53 suppresses cyclin A expression

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28 November 2018

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression

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28 November 2018

Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle

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28 November 2018

The role of cellular transcription factor E2F in the regulation of cdc2 mRNA expression and cell cycle control of human hematopoietic cells.

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28 November 2018

34 Analysis of methylation and chromatin structure

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28 November 2018

Methylation analysis by genomic sequencing of 5' region of mouse Pgk-1 gene and a cautionary note concerning the method

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28 November 2018

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ordering S phase and M phase in the cell cycle

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https://pubmed.ncbi.nlm.nih.gov/8524257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitosis in transition

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https://pubmed.ncbi.nlm.nih.gov/8524257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement

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https://pubmed.ncbi.nlm.nih.gov/8524257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cdc2 gene expression at the G1 to S transition in human T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8524257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of human cyclin E with a periodic G1-S phase protein kinase

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https://pubmed.ncbi.nlm.nih.gov/8524257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members

1 reference

https://pubmed.ncbi.nlm.nih.gov/8524257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1128/MCB.15.12.6901

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