Sequence-specific targeting of nuclear signal transduction pathways by homeodomain proteins (Q24652195)

1

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K J Simon

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K Brennan

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M Gilman

Molecular and Cellular Biology

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language of work or name

English

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publication date

June 1995

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published in

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volume

15

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issue

6

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page(s)

3318-26

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cites work

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Synergism in ternary complex formation between the dimeric glycoprotein p67SRF, polypeptide p62TCF and the c-fos serum response element

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Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor

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Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

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Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions

7 April 2017

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Rapid and efficient site-specific mutagenesis without phenotypic selection

7 April 2017

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Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain

7 April 2017

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7 April 2017

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Homeobox genes and axial patterning

7 April 2017

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The structure and function of the homeodomain

7 April 2017

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Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation

7 April 2017

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The war of the whorls: genetic interactions controlling flower development

7 April 2017

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Functional specificity of the homeodomain protein fushi tarazu: the role of DNA-binding specificity in vivo

7 April 2017

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Heterodimerization of the yeast MATa1 and MAT alpha 2 proteins is mediated by two leucine zipper-like coiled-coil motifs.

28 September 2017

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Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3.

28 September 2017

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The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences

28 September 2017

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Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila

28 September 2017

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Understanding the homeodomain

28 September 2017

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Cooperative dimerization of paired class homeo domains on DNA.

28 September 2017

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MAT alpha 1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes

28 September 2017

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Identification of a DNA segment that is necessary and sufficient for alpha-specific gene control in Saccharomyces cerevisiae: implications for regulation of alpha-specific and a-specific genes

28 September 2017

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Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression

28 September 2017

1 reference

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Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter

28 September 2017

1 reference

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elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints

28 September 2017

1 reference

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The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

28 September 2017

1 reference

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A sensitive method for the determination of protein-DNA binding specificities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Combinatorial associations of regulatory proteins and the control of cell type in yeast

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The SRE: a growth factor responsive transcriptional regulator

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

What determines the specificity of action of Drosophila homeodomain proteins?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Cell-type specific multiprotein complex formation over the c-fos serum response element in vivo: ternary complex formation is not required for the induction of c-fos

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The DNA binding and oligomerization domain of MCM1 is sufficient for its interaction with other regulatory proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

A Genetic Model for Interaction of the Homeodomain Recognition Helix with DNA

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The SRF and MCM1 transcription factors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Recognition of the surface of a homeo domain protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Common signal transduction system shared by STE2 and STE3 in haploid cells of Saccharomyces cerevisiae: autocrine cell-cycle arrest results from forced expression of STE2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Functional analysis of a growth factor-responsive transcription factor complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Differential positive control by Oct-1 and Oct-2: activation of a transcriptionally silent motif through Oct-1 and VP16 corecruitment

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The yeast cell-type-specific repressor alpha 2 acts cooperatively with a non-cell-type-specific protein.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Activation of the U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elements

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

A homeodomain substitution changes the regulatory specificity of the deformed protein in Drosophila embryos

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Functional dissection of Ultrabithorax proteins in D. melanogaster.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Distinct protein targets for signals acting at the c-fos serum response element

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Induction by NGF of Meiotic Maturation of Xenopus Oocytes Expressing the trk Proto-Oncogene Product

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Mapping functional specificity in the Dfd and Ubx homeo domains

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Genetic Control of Flower Development by Homeotic Genes in Antirrhinum majus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Torso, a receptor tyrosine kinase required for embryonic pattern formation, shares substrates with the sevenless and EGF-R pathways in Drosophila

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The sevenless signalling cassette mediates Drosophila EGF receptor function during epidermal development.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The carboxy-terminal tail of the homeo domain protein alpha 2 is required for function with a second homeo domain protein.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

extradenticle raises the DNA binding specificity of homeotic selector gene products

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230565

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7760827

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Yeast peptide pheromones, a-factor and alpha-factor, activate a common response mechanism in their target cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7760827