Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis (Q24669697)

2

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S Roy

3

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D W Nicholson

4

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N A Thornberry

5

0 references

L A Casciola-Rosen

6

0 references

A Rosen

Mitochondrial release of caspase-2 and -9 during the apoptotic process

7

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language of work or name

English

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publication date

1 May 2000

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published in

Journal of Cell Biology

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volume

149

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issue

3

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page(s)

603-12

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cites work

1 reference

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A role for giantin in docking COPI vesicles to Golgi membranes

7 April 2017

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Molecular characterization of GCP170, a 170-kDa protein associated with the cytoplasmic face of the Golgi membrane

7 April 2017

1 reference

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

7 April 2017

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Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa

7 April 2017

1 reference

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Macrogolgin--a new 376 kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections

7 April 2017

1 reference

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Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D

7 April 2017

1 reference

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TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1

7 April 2017

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Death receptors: signaling and modulation

7 April 2017

1 reference

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A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors

7 April 2017

1 reference

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Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

7 April 2017

1 reference

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The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner

7 April 2017

1 reference

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p230 is associated with vesicles budding from the trans-Golgi network

7 April 2017

1 reference

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RAIDD is a new 'death' adaptor molecule

7 April 2017

1 reference

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

7 April 2017

1 reference

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Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

7 April 2017

1 reference

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Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Activation of caspase-2 in apoptosis

7 April 2017

1 reference

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7 April 2017

Caspases: enemies within

1 reference

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Caspases: killer proteases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

7 April 2017

1 reference

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Caspase knockouts: matters of life and death.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Structural elements common to mitosis and apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

B cell apoptosis triggered by antigen receptor ligation proceeds via a novel caspase-dependent pathway.

28 September 2017

1 reference

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The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Mammalian phosphatidylinositol transfer proteins: emerging roles in signal transduction and vesicular traffic.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Deciphering the pathways of life and death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Activation of membrane-associated procaspase-3 is regulated by Bcl-2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Toll, a new piece in the puzzle of innate immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Defects in regulation of apoptosis in caspase-2-deficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Ceramide accumulation uncovers a cycling pathway for the cis-Golgi network marker, infectious bronchitis virus M protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Oligomerization of a membrane protein correlates with its retention in the Golgi complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Inhibition of apoptosis by the expression of antisense Nedd2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Detection of pro-caspase-3 in cytosol and mitochondria of various tissues

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Autoproteolytic activation of pro-caspases by oligomerization

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Dimerization and autoprocessing of the Nedd2 (caspase-2) precursor requires both the prodomain and the carboxyl-terminal regions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Caspases: intracellular signaling by proteolysis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Processing of the Nedd2 precursor by ICE-like proteases and granzyme B.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174848

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

30 May 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.3.603

Cloning and molecular characterization of cDNA encoding a mouse male-enhanced antigen-2 (Mea-2): a putative family of the Golgi autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.3.603

Purification and catalytic properties of human caspase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.3.603

21 January 2018

Ceramide and apoptosis

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.3.603

Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10791974

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.149.3.603

1 reference

1 reference

1 reference

PubMed publication ID

10791974

1 reference