Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor (Q24683260)

19 October 2023

Wen Xie

1

Wen

Xie

1 reference

19 October 2023

Mei-Fei Yeuh

2

Mei-Fei

Yeuh

1 reference

19 October 2023

Anna Radominska-Pandya

3

Anna

Radominska-Pandya

1 reference

19 October 2023

Simrat P S Saini

4

Simrat P S

Saini

1 reference

19 October 2023

Yoichi Negishi

5

Yoichi

Negishi

1 reference

19 October 2023

Bobbie Sue Bottroff

6

Bobbie Sue

Bottroff

1 reference

19 October 2023

Geraldine Y Cabrera

7

Geraldine Y

Cabrera

1 reference

19 October 2023

Robert H Tukey

8

Robert H

Tukey

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

0 references

publication date

1 April 2003

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published in

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volume

100

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issue

7

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page(s)

4150-5

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cites work

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

1 reference

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Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

7 April 2017

1 reference

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Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

7 April 2017

1 reference

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An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

7 April 2017

1 reference

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Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

In vitro induction of bilirubin conjugation in primary rat hepatocyte culture

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Orphan nuclear receptors: the exotics of xenobiotics.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

N-glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N_hydroxy-PhIP by specific human UDP-glucuronosyltransferases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Glucuronidation of 6 alpha-hydroxy bile acids by human liver microsomes

28 September 2017

1 reference

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Characterization of human microsomal cytochrome P-450 enzymes

28 September 2017

1 reference

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In vitro and in vivo biotransformation and covalent binding of benzo(a)pyrene in Gunn and RHA rats with a genetic deficiency in bilirubin uridine diphosphate-glucuronosyltransferase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Unexpected clinical remission of cholestasis after rifampicin therapy in patients with normal or slightly increased levels of gamma-glutamyl transpeptidase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153063

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0438010100

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0438010100

Genetic inheritance of Gilbert's syndrome

21 January 2018

1 reference

12 December 2020

Coordinate induction by antioxidants of UDP-glucuronosyltransferase UGT1A6 and the apical conjugate export pump MRP2 (multidrug resistance protein 2) in Caco-2 cells

1 reference

12 December 2020

Characterization of the uridine diphosphate-glucuronosyltransferase-catalyzing thyroid hormone glucuronidation in man

1 reference

12 December 2020

Enhancement of glucuronide-conjugating capacity in a hyperbilirubinemic infant due to apparent enzyme induction by phenobarbital

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0438010100

1 reference

ADS bibcode

2003PNAS..100.4150X

0 references

1 reference

1 reference

1 reference