A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes (Q24804876)

2

0 references

Enrique Perez-Cardenas

3

0 references

Lucely Cetina

4

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Alma Revilla-Vazquez

5

0 references

Lucía Taja-Chayeb

6

0 references

Alma Chavez-Blanco

7

0 references

Enrique Angeles

8

0 references

Gustavo Cabrera

9

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Karina Sandoval

10

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Catalina Trejo-Becerril

11

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Jose Chanona-Vilchis

12

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Alfonso Duenas-González

Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: its relationship to clinical outcome

13

0 references

language of work or name

English

0 references

publication date

2005

0 references

published in

BMC Cancer

0 references

volume

5

0 references

issue

1

0 references

page(s)

44

0 references

cites work

1 reference

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

7 April 2017

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

7 April 2017

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

7 April 2017

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Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells

7 April 2017

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

7 April 2017

1 reference

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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

7 April 2017

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Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

7 April 2017

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

7 April 2017

1 reference

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The history of cancer epigenetics

7 April 2017

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Role for DNA methylation in genomic imprinting

7 April 2017

1 reference

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

7 April 2017

1 reference

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Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies.

7 April 2017

1 reference

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Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis

28 September 2017

1 reference

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Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations

28 September 2017

1 reference

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A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly

28 September 2017

1 reference

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Capillary electrophoretic analysis of genomic DNA methylation levels

28 September 2017

1 reference

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DNA methyltransferase inhibitors-state of the art.

28 September 2017

1 reference

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DNA methylation and gene silencing in cancer: which is the guilty party?

28 September 2017

1 reference

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A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes

28 September 2017

1 reference

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DNA methylation, methyltransferases, and cancer

28 September 2017

1 reference

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Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

28 September 2017

1 reference

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

28 September 2017

1 reference

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Modified oligonucleotides as bona fide antagonists of proteins interacting with DNA. Hairpin antagonists of the human DNA methyltransferase

28 September 2017

1 reference

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Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide

28 September 2017

1 reference

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Effects of DNA methylation on DNA-binding proteins and gene expression.

28 September 2017

1 reference

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Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

28 September 2017

1 reference

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Loss of methylation activates Xist in somatic but not in embryonic cells

28 September 2017

1 reference

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Number of CpG islands and genes in human and mouse

28 September 2017

1 reference

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The essentials of DNA methylation

28 September 2017

1 reference

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Drug-induced DNA hypermethylation: a potential mediator of acquired drug resistance during cancer chemotherapy

28 September 2017

1 reference

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Comparison of the in vitro cytotoxicity (L1210) of 5-aza-2'-deoxycytidine with its therapeutic and toxic effects in mice

28 September 2017

1 reference

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Determination of 5-methyl-cytosine and cytosine in tumor DNA of cancer patients

30 May 2018

1 reference

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Clinical pharmacokinetics of vasodilators. Part II.

21 January 2018

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https://api.crossref.org/works/10.1186%2F1471-2407-5-44

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-44

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-44

Modulation of Igf2 genomic imprinting in mice induced by 5-azacytidine, an inhibitor of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-44

Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-44

Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131894

Phase I trial of continuous infusion 5-aza-2'-deoxycytidine

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131894

A Genome-Wide Screen for Normally Methylated Human CpG Islands That Can Identify Novel Imprinted Genes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131894

Aberrant methylation during cervical carcinogenesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131894

Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix

28 November 2018

1 reference

12 December 2020

Variability of plasma hydralazine concentrations in male hypertensive patients

1 reference

12 December 2020

Mechanisms of drug‐induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo

1 reference

12 December 2020

Acetylator phenotypes: allele frequency in northwestern Argentina and review of acetylator distribution in the Americas

1 reference

12 December 2020

5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model

1 reference

12 December 2020

A sensitive new method for rapid detection of abnormal methylation patterns in global DNA and within CpG islands

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-5-44

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jeea2jnh2reb3p6gus2hqm2ouu

30 July 2022

Dimensions Publication ID

1001955909

0 references

Fatcat ID

release_jeea2jnh2reb3p6gus2hqm2ouu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jeea2jnh2reb3p6gus2hqm2ouu

30 July 2022

OpenCitations bibliographic resource ID

3373151

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://api.fatcat.wiki/v0/release/jeea2jnh2reb3p6gus2hqm2ouu

30 July 2022

https://api.fatcat.wiki/v0/release/jeea2jnh2reb3p6gus2hqm2ouu

PubMed publication ID

1 reference

30 July 2022