The potential utility of tight junction regulation in celiac disease: focus on larazotide acetate (Q26771888)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26770266%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

The potential utility of tight junction regulation in celiac disease: focus on larazotide acetate (English)

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5 March 2020

3

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5 March 2020

author name string

Shahryar Khaleghi

series ordinal

1

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5 March 2020

Josephine M Ju

series ordinal

2

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5 March 2020

Joseph A Murray

series ordinal

4

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5 March 2020

language of work or name

English

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publication date

1 January 2016

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Therapeutic Advances in Gastroenterology

5 March 2020

published in

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5 March 2020

volume

9

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5 March 2020

issue

1

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5 March 2020

page(s)

37-49

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Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3

5 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Occludin: a novel integral membrane protein localizing at tight junctions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Larazotide acetate for persistent symptoms of celiac disease despite a gluten-free diet: a randomized controlled trial.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Modeling of celiac disease immune response and the therapeutic effect of potential drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Larazotide acetate in patients with coeliac disease undergoing a gluten challenge: a randomised placebo-controlled study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Review article: coeliac disease, new approaches to therapy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Urine sugars for in vivo gut permeability: validation and comparisons in irritable bowel syndrome-diarrhea and controls

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Increased bacterial translocation in gluten-sensitive mice is independent of small intestinal paracellular permeability defect

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Electrophysiological characterization of claudin ion permeability using stably transfected epithelial cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Measuring size-dependent permeability of the tight junction using PEG profiling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Regulation of tight junction permeability by intestinal bacteria and dietary components

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Classification and management of refractory coeliac disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Mucosal recovery and mortality in adults with celiac disease after treatment with a gluten-free diet

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Mechanism of interferon-gamma-induced increase in T84 intestinal epithelial tight junction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Pilot study on the effect of linaclotide in patients with chronic constipation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

EGF receptor transactivation and MAP kinase mediate proteinase-activated receptor-2-induced chloride secretion in intestinal epithelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Adherens and tight junctions: structure, function and connections to the actin cytoskeleton

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Alterations in intestinal permeability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Duodenal histology in patients with celiac disease after treatment with a gluten-free diet

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Coeliac disease: dissecting a complex inflammatory disorder

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Gluten-free diet and quality of life in patients with screen-detected celiac disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Intestinal permeation and gastrointestinal disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Detecting celiac disease in your patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Intestinal permeability: an overview

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Intestinal permeability in patients with coeliac disease and relatives of patients with coeliac disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Morphological and biochemical studies of a naturally occurring enteropathy in the Irish setter dog: a comparison with coeliac disease in man.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Role of calcium in tight junction formation between epithelial cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Abnormal permeability precedes the development of a gluten sensitive enteropathy in Irish setter dogs

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.

31 May 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Larazotide acetate regulates epithelial tight junctions in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Larazotide acetate promotes tight junction assembly in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Intentional and inadvertent non-adherence in adult coeliac disease. A cross-sectional survey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Complete recovery of intestinal mucosa occurs very rarely in adult coeliac patients despite adherence to gluten-free diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Polymeric binders suppress gliadin-induced toxicity in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Reduced quality of life in coeliac disease is more strongly associated with depression than gastrointestinal symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Epithelial Tight Junction Structure in the Jejunum of Children with Acute and Treated Celiac Sprue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756283X15616576

Food labeling: gluten-free labeling of foods. Final rule

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4699279

Affinity purification and partial characterization of the zonulin/zonula occludens toxin (Zot) receptor from human brain

28 November 2018

1 reference

12 December 2020

It is the compliance, not milligrams of gluten, that is essential in the treatment of celiac disease

1 reference

12 December 2020

Pathways of gliadin transport in celiac disease

1 reference

12 December 2020

Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease

1 reference

12 December 2020

Transmembrane proteins of tight junctions

1 reference

12 December 2020

High rate of gastrointestinal symptoms in celiac patients living on a gluten-free diet: controlled study

1 reference

12 December 2020

Increased gastric and intestinal permeability in patients with Crohn's disease

1 reference

12 December 2020

A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease

1 reference

12 December 2020

Paracellular versus Transcellular Intestinal Permeability to Gliadin Peptides in Active Celiac Disease

1 reference

12 December 2020

Identifiers

DOI

10.1177/1756283X15616576

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26770266%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26770266%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

26770266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26770266%20AND%20SRC:MED&resulttype=core&format=json