Modeling psychiatric disorders for developing effective treatments (Q26784269)

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English	Modeling psychiatric disorders for developing effective treatments	scientific article

Statements

instance of

scholarly article

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title

Modeling psychiatric disorders for developing effective treatments (English)

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author name string

Tobias Kaiser

series ordinal

1

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Guoping Feng

series ordinal

2

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language of work or name

English

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publication date

September 2015

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published in

Nature Medicine

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volume

21

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issue

9

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page(s)

979-88

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cites work

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Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

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Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

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CNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in Drosophila

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Common genetic variants on 5p14.1 associate with autism spectrum disorders

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Disruption of the neurexin 1 gene is associated with schizophrenia

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Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

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Genome-scale neurogenetics: methodology and meaning

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7 April 2017

High resolution magnetic resonance imaging for characterization of the neuroligin-3 knock-in mouse model associated with autism spectrum disorder

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7 April 2017

Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions

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7 April 2017

The endophenotype concept in psychiatry: etymology and strategic intentions

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7 April 2017

Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin

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7 April 2017

Heritability estimates for psychotic disorders: the Maudsley twin psychosis series

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SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

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7 April 2017

AMPAKINE enhancement of social interaction in the BTBR mouse model of autism

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7 April 2017

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

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Cerebral organoids model human brain development and microcephaly

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Research domain criteria (RDoC): toward a new classification framework for research on mental disorders

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A new initiative on precision medicine

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7 April 2017

Structural and molecular interrogation of intact biological systems

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7 April 2017

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

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Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

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Self-organizing optic-cup morphogenesis in three-dimensional culture

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7 April 2017

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

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7 April 2017

Animal models of neuropsychiatric disorders

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7 April 2017

Autism-like behavioral phenotypes in BTBR T+tf/J mice

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Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

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7 April 2017

Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia

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7 April 2017

Learning From Animal Models of Obsessive-Compulsive Disorder

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28 September 2017

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

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28 September 2017

FAAH genetic variation enhances fronto-amygdala function in mouse and human

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28 September 2017

From circuits to behaviour in the amygdala

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28 September 2017

Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation

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28 September 2017

Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons

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Prioritization of neurodevelopmental disease genes by discovery of new mutations

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28 September 2017

A polygenic burden of rare disruptive mutations in schizophrenia

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28 September 2017

De novo mutations in schizophrenia implicate synaptic networks

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Clinical development success rates for investigational drugs

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28 September 2017

Identifying essential cell types and circuits in autism spectrum disorders.

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28 September 2017

Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism

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28 September 2017

Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission

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28 September 2017

SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties

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28 September 2017

Mouse models of gene-environment interactions in schizophrenia

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28 September 2017

Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors

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28 September 2017

Repeated cortico-striatal stimulation generates persistent OCD-like behavior

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28 September 2017

Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins

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28 September 2017

Criteria of validity for animal models of psychiatric disorders: focus on anxiety disorders and depression.

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28 September 2017

Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice

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28 September 2017

Genetic architecture in autism spectrum disorder

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28 September 2017

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

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28 September 2017

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

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28 September 2017

Stepwise evolution of stable sociality in primates

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28 September 2017

Reduced sleep spindles and spindle coherence in schizophrenia: mechanisms of impaired memory consolidation?

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28 September 2017

A role for glia in the progression of Rett's syndrome

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28 September 2017

Abnormal medial prefrontal cortex resting-state connectivity in bipolar disorder and schizophrenia

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28 September 2017

Thalamic dysfunction in schizophrenia suggested by whole-night deficits in slow and fast spindles

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28 September 2017

Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders

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28 September 2017

Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia

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28 September 2017

Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.

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28 September 2017

A genome-wide linkage and association scan reveals novel loci for autism

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28 September 2017

Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

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28 September 2017

Forward frontal fields: phylogeny and fundamental function

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28 September 2017

Cortical source estimates of gamma band amplitude and phase are different in schizophrenia

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28 September 2017

Gene-environment interactions in psychiatry: joining forces with neuroscience

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28 September 2017

A review of diffusion tensor imaging studies in schizophrenia

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28 September 2017

Neural synchrony indexes disordered perception and cognition in schizophrenia

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28 September 2017

Regionally localized thinning of the cerebral cortex in schizophrenia

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28 September 2017

Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.

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28 September 2017

Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder

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28 September 2017

The basal ganglia

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NM.3935

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1657054

Dimensions Publication ID

1043042992

0 references

OpenCitations bibliographic resource ID

1657054

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1657054

PMC publication ID

4886231

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1657054

PubMed publication ID

26340119

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1657054

 

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