Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads (Q26827667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22710170%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads (English)

2 references

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5 February 2020

1

1 reference

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5 February 2020

Masafumi Inui

series ordinal

2

1 reference

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5 February 2020

author name string

Stuart J Newfeld

series ordinal

3

1 reference

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5 February 2020

language of work or name

1 reference

24 March 2012

1 reference

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5 February 2020

2 references

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5 February 2020

volume

586

2 references

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5 February 2020

issue

14

2 references

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5 February 2020

page(s)

1913-1920

1 reference

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Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

5 February 2020

cites work

1 reference

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USP15 is a deubiquitylating enzyme for receptor-activated SMADs

7 April 2017

1 reference

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RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

7 April 2017

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Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells

7 April 2017

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TRIM24 links a non-canonical histone signature to breast cancer

7 April 2017

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TIF1gamma controls erythroid cell fate by regulating transcription elongation

7 April 2017

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Trim24 targets endogenous p53 for degradation

7 April 2017

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Regulation of planar cell polarity by Smurf ubiquitin ligases

7 April 2017

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FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

7 April 2017

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The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

7 April 2017

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Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

7 April 2017

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Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation

7 April 2017

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Ubiquitination regulates PTEN nuclear import and tumor suppression

7 April 2017

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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

7 April 2017

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The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis

7 April 2017

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Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling

7 April 2017

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Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

7 April 2017

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Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD

7 April 2017

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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

7 April 2017

1 reference

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Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

7 April 2017

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

7 April 2017

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A Poised Chromatin Platform for TGF-β Access to Master Regulators

7 April 2017

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Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling

7 April 2017

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The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization

7 April 2017

1 reference

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Breaking the chains: structure and function of the deubiquitinases

7 April 2017

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Control of Smad7 stability by competition between acetylation and ubiquitination

7 April 2017

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Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

7 April 2017

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Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia

7 April 2017

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Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

7 April 2017

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Smad transcription factors

7 April 2017

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Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

7 April 2017

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Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription

7 April 2017

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

7 April 2017

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Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development

7 April 2017

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Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

7 April 2017

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Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo

7 April 2017

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In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis

7 April 2017

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dSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2.

7 April 2017

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Isolation and characterization of the mouse ubiquitin-specific protease Usp15

7 April 2017

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Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

7 April 2017

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Physiological functions of the HECT family of ubiquitin ligases

7 April 2017

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

7 April 2017

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The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway

7 April 2017

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7 April 2017

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Phosphorylation of Mad controls competition between wingless and BMP signaling

28 September 2017

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Wg signaling via Zw3 and mad restricts self-renewal of sensory organ precursor cells in Drosophila

28 September 2017

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Recruitment of TIF1γ to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities

28 September 2017

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TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

28 September 2017

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28 September 2017

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Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

28 September 2017

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28 September 2017

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Early phase TGFβ receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas

28 September 2017

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TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

28 September 2017

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Regulation of TGF-beta family signaling by E3 ubiquitin ligases

28 September 2017

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Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

28 September 2017

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Roles of mono-ubiquitinated Smad4 in the formation of Smad transcriptional complexes.

28 September 2017

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Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

28 September 2017

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TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

28 September 2017

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Ubiquitin-dependent regulation of TGFbeta signaling in cancer

28 September 2017

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A FoxO-Smad synexpression group in human keratinocytes

28 September 2017

1 reference

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MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation

28 September 2017

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The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling

28 September 2017

1 reference

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Signaling through monoubiquitination.

28 September 2017

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Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile.

28 September 2017

1 reference

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Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

28 September 2017

1 reference

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Differential ubiquitination defines the functional status of the tumor suppressor Smad4.

28 September 2017

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A specific protein substrate for a deubiquitinating enzyme: Liquid facets is the substrate of Fat facets

28 September 2017

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Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads

28 September 2017

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The gata1/pu.1 lineage fate paradigm varies between blood populations and is modulated by tif1γ.

28 September 2017

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The Fused/Smurf complex controls the fate of Drosophila germline stem cells by generating a gradient BMP response

31 May 2018

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Highwire regulates presynaptic BMP signaling essential for synaptic growth.

31 May 2018

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Lysine conservation and context in TGFbeta and Wnt signaling suggest new targets and general themes for posttranslational modification

21 January 2018

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Crystal Structure of a Phosphorylated Smad2

21 January 2018

1 reference

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Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.03.037

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.03.037

Ubiquitination-dependent mechanisms regulate synaptic growth and function.

21 January 2018

1 reference

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A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

21 January 2018

1 reference

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Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.03.037

The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.03.037

Fat facets deubiquitylation of Medea/Smad4 modulates interpretation of a Dpp morphogen gradient.

21 January 2018

1 reference

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Ubiquitin signalling in DNA replication and repair

28 November 2018

1 reference

12 December 2020

Adult hematopoiesis is regulated by TIF1γ, a repressor of TAL1 and PU.1 transcriptional activity

1 reference

12 December 2020

The loss of mdm2 induces p53-mediated apoptosis

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12 December 2020

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

1 reference

12 December 2020

Changing venues for tumour suppression: balancing destruction and localization by monoubiquitylation

1 reference

12 December 2020

10.1016/J.FEBSLET.2012.03.037

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22710170%20AND%20SRC:MED&resulttype=core&format=json

release_o5b35wi7azbobdt5rv2umdrovm

5 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/o5b35wi7azbobdt5rv2umdrovm

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22710170%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

22710170

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22710170%20AND%20SRC:MED&resulttype=core&format=json