Reprogramming pancreatic cells to β cells (Q26863661)

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author name string

Monica Courtney

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Fabio Avolio

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Nouha Ben-Othman

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Anja Pfeifer

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Elisabet Gjernes

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Biljana Faurite

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publication date

2013

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29

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issue

8-9

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page(s)

749-55

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Specifying pancreatic endocrine cell fates.

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The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

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Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

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Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells

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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

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In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells

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Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration.

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

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Differentiation of pluripotent stem cells into pancreatic lineages

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The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

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10.1051/MEDSCI/2013298014

21 January 2018

Identifiers

DOI

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Erudit article ID

2013298014

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PubMed publication ID

24005630

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