Activation of cell stress response pathways by Shiga toxins (Q27027623)

language of work or name

1 reference

January 2012

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published in

Cellular Microbiology

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volume

14

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issue

1

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page(s)

1-9

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Shiga toxin 2 targets the murine renal collecting duct epithelium

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Intracellular signaling by the unfolded protein response

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

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Inhibition of the unfolded protein response by ricin a-chain enhances its cytotoxicity in mammalian cells

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Differential response of the human renal proximal tubular epithelial cell line HK-2 to Shiga toxin types 1 and 2.

28 September 2017

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Influence of Escherichia coli shiga toxin on the mammalian central nervous system

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Global transcriptional response of macrophage-like THP-1 cells to Shiga toxin type 1

28 September 2017

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Induction of apoptosis by Shiga toxins

28 September 2017

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Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes

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Shiga toxins--from cell biology to biomedical applications

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Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals

28 September 2017

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Caspase-8-mediated cleavage of Bid and protein phosphatase 2A-mediated activation of Bax are necessary for Verotoxin-1-induced apoptosis in Burkitt's lymphoma cells

28 September 2017

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Bcl-2 regulates the onset of shiga toxin 1-induced apoptosis in THP-1 cells

28 September 2017

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Shiga toxin and lipopolysaccharide induce platelet-leukocyte aggregates and tissue factor release, a thrombotic mechanism in hemolytic uremic syndrome

28 September 2017

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Protein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L.

28 September 2017

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The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain in Saccharomyces cerevisiae

28 September 2017

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Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein

28 September 2017

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Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways

28 September 2017

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ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.

28 September 2017

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Ricin inhibits activation of the unfolded protein response by preventing splicing of the HAC1 mRNA.

28 September 2017

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PKR is a novel functional direct player that coordinates skeletal muscle differentiation via p38MAPK/AKT pathways.

28 September 2017

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Shiga toxin induces tubular membrane invaginations for its uptake into cells

28 September 2017

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The endoplasmic reticulum and the unfolded protein response

28 September 2017

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Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells

28 September 2017

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Stx-phages: drivers and mediators of the evolution of STEC and STEC-like pathogens

28 September 2017

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Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1

28 September 2017

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Shiga toxin-producing Escherichia coli: an overview

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Entry of protein toxins into mammalian cells by crossing the endoplasmic reticulum membrane: co-opting basic mechanisms of endoplasmic reticulum-associated degradation

28 September 2017

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Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line

28 September 2017

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Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome

28 September 2017

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Comparative evaluation of apoptosis induced by Shiga toxin 1 and/or lipopolysaccharides in human monocytic and macrophage-like cells.

28 September 2017

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Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome

28 September 2017

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Regulation of proinflammatory cytokine expression by Shiga toxin 1 and/or lipopolysaccharides in the human monocytic cell line THP-1

28 September 2017

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Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.

28 September 2017

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Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells

28 September 2017

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Shiga toxin-2 triggers endothelial leukocyte adhesion and transmigration via NF-kappaB dependent up-regulation of IL-8 and MCP-1.

28 September 2017

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Shiga toxin 1-induced activation of c-Jun NH(2)-terminal kinase and p38 in the human monocytic cell line THP-1: possible involvement in the production of TNF-alpha.

28 September 2017

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Shiga toxins induce, superinduce, and stabilize a variety of C-X-C chemokine mRNAs in intestinal epithelial cells, resulting in increased chemokine expression

28 September 2017

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Novel role for JNK as a stress-activated Bcl2 kinase

28 September 2017

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Shiga toxin-induced tumor necrosis factor alpha expression: requirement for toxin enzymatic activity and monocyte protein kinase C and protein tyrosine kinases

28 September 2017

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mkp-1 encoding mitogen-activated protein kinase phosphatase 1, a verotoxin 1 responsive gene, detected by differential display reverse transcription-PCR in Caco-2 cells

28 September 2017

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Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.

28 September 2017

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Shiga toxin type 1 activates tumor necrosis factor-alpha gene transcription and nuclear translocation of the transcriptional activators nuclear factor-kappaB and activator protein-1.

28 September 2017

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Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

28 September 2017

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Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.

28 September 2017

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Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes

28 September 2017

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The catalytic subunit of shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain

31 May 2018

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Shiga toxin is transported from the endoplasmic reticulum following interaction with the luminal chaperone HEDJ/ERdj3.

31 May 2018

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Bcl-2 Phosphorylation by p38 MAPK

31 May 2018

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Shiga toxin B-subunit binds to the chaperone BiP and the nucleolar protein B23.

21 January 2018

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Structure of shiga toxin type 2 (Stx2) from Escherichia coli O157:H7.

21 January 2018

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Furin-induced cleavage and activation of Shiga toxin

21 January 2018

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Membrane cytosolic translocation of verotoxin A1 subunit in target cells.

21 January 2018

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Bacteriophage control of Shiga toxin 1 production and release by Escherichia coli.

21 January 2018

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Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages fromEscherichia coli933

21 January 2018

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Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum

21 January 2018

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10.1111/J.1462-5822.2011.01684.X

21 January 2018

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

21899699

1 reference