Tau-targeted treatment strategies in Alzheimer's disease (Q27023429)

British Journal of Pharmacology

published in

1 reference

volume

165

1 reference

issue

5

1 reference

page(s)

1246-59

1 reference

A role for FKBP52 in Tau protein function

cites work

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Transmission and spreading of tauopathy in transgenic mouse brain

21 March 2017

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Rivastigmine for Alzheimer's disease

21 March 2017

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Interaction of tau protein with the dynactin complex

21 March 2017

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21 March 2017

Memantine for dementia

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Galantamine for Alzheimer's disease and mild cognitive impairment

21 March 2017

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Donepezil for dementia due to Alzheimer's disease

21 March 2017

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Tau interacts with src-family non-receptor tyrosine kinases

21 March 2017

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Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

21 March 2017

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Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

21 March 2017

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A protein factor essential for microtubule assembly

21 March 2017

1 reference

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Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 March 2017

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 March 2017

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Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

21 March 2017

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CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

21 March 2017

1 reference

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Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice

21 March 2017

1 reference

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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 March 2017

1 reference

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Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha

21 March 2017

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Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 March 2017

1 reference

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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

7 April 2017

1 reference

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Neurodegenerative tauopathies

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

The distribution of tau in the mammalian central nervous system

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

28 September 2017

The many faces of tau

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Amyloid-β and tau--a toxic pas de deux in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Immunotherapy for Alzheimer's disease

28 September 2017

1 reference

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Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model

28 September 2017

1 reference

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Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

The role of tau kinases in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Probing the biology of Alzheimer's disease in mice

28 September 2017

1 reference

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Three repeat isoforms of tau inhibit assembly of four repeat tau filaments

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Oxidative stress: emerging mitochondrial and cellular themes and variations in neuronal injury.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Promoting successful cognitive aging: a comprehensive review

28 September 2017

1 reference

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Sertraline for the treatment of depression in Alzheimer disease: week-24 outcomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Interneuronal transfer of human tau between Lamprey central neurons in situ

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Tau-focused immunotherapy for Alzheimer's disease and related tauopathies.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Effectiveness of donepezil in reducing clinical worsening in patients with mild-to-moderate alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Management of agitation and aggression associated with Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Propagation of tau misfolding from the outside to the inside of a cell.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

28 September 2017

1 reference

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Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

28 September 2017

1 reference

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Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments

28 September 2017

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ALS and FTLD: two faces of TDP-43 proteinopathy

28 September 2017

1 reference

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Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

28 September 2017

1 reference

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Animal models of Alzheimer's disease and frontotemporal dementia

28 September 2017

1 reference

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Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention

28 September 2017

1 reference

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Improvement in behavioural symptoms in patients with moderate to severe Alzheimer's disease by memantine: a pooled data analysis

28 September 2017

1 reference

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Rhodanine-based tau aggregation inhibitors in cell models of tauopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Tau phosphorylation sites work in concert to promote neurotoxicity in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Beta-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Tau phosphorylation, aggregation, and cell toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Neuroleptic drugs in dementia: benefits and harm

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Different tau epitopes define Abeta42-mediated tau insolubility

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Functional interactions of tau and their relevance for Alzheimer's disease.

28 September 2017

1 reference

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Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reaction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Posttranslational modifications of tau--role in human tauopathies and modeling in transgenic animals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet

28 September 2017

1 reference

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Role for glyoxalase I in Alzheimer's disease.

28 September 2017

1 reference

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Phosphorylation of tau by fyn: implications for Alzheimer's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

14-3-3 connects glycogen synthase kinase-3 beta to tau within a brain microtubule-associated tau phosphorylation complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Immature human NT2 cells grafted into mouse brain differentiate into neuronal and glial cell types.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Tau filament formation in transgenic mice expressing P301L tau.

28 September 2017

1 reference

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Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Staging of Alzheimer's disease-related neurofibrillary changes

28 September 2017

1 reference

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31P nuclear magnetic resonance (NMR) spectroscopy of brain in aging and Alzheimer's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Microtubule-associated proteins and the determination of neuronal form.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Developmentally regulated alternative splicing of mRNAs encoding N-terminal tau variants in the rat hippocampus: structural and functional implications

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Alzheimer's disease: genotypes, phenotypes, and treatments

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Analysis of microtubule-associated protein tau glycation in paired helical filaments.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Microtubule-associated protein function: lessons from expression in Spodoptera frugiperda cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Microtubule formation and neurite growth in cerebellar macroneurons which develop in vitro: evidence for the involvement of the microtubule-associated proteins, MAP-1a, HMW-MAP2 and Tau

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

31 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Proteasomal degradation of tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Naturally occurring autoantibodies against beta-amyloid: investigating their role in transgenic animal and in vitro models of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Compartmentalized tau hyperphosphorylation and increased levels of kinases in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Active immunization trial in Abeta42-injected P301L tau transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Tau is a candidate gene for chromosome 17 frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Tau protein pathology in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Glycogen synthase kinase-3beta is complexed with tau protein in brain microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Challenges in the conduct of disease-modifying trials in AD: practical experience from a phase 2 trial of Tau-aggregation inhibitor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Tau and transgenic animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01713.X

Memantine for agitation/aggression and psychosis in moderately severe to severe Alzheimer's disease: a pooled analysis of 3 studies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

The femtomolar-acting NAP interacts with microtubules: Novel aspects of astrocyte protection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372713

Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

28 November 2018

1 reference

12 December 2020

Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation

1 reference

12 December 2020

TDP-43 and FUS: a nuclear affair

1 reference

12 December 2020

Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage

1 reference

12 December 2020

Tau is widely expressed in rat tissues

1 reference

12 December 2020

10.1111/J.1476-5381.2011.01713.X

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

22044248

1 reference