The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in Drosophila (Q27305012)

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English	The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in Drosophila	scientific article

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31 March 2020

The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in Drosophila (English)

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31 March 2020

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Blastoderm-specific gene 25D Dmel_CG14025

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GOA release 2020-03-11

Seckel syndrome

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based on heuristic

inferred from title

7

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31 March 2020

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Yiming Zheng

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31 March 2020

Vito Mennella

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31 March 2020

Steven Marks

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31 March 2020

Jill Wildonger

4

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31 March 2020

Esraa Elnagdi

5

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31 March 2020

David Agard

6

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31 March 2020

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6 April 2016

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31 March 2020

Molecular Biology of the Cell

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31 March 2020

27

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31 March 2020

11

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31 March 2020

1740-1752

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31 March 2020

CtIP Mutations Cause Seckel and Jawad Syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

CEP152 is a genome maintenance protein disrupted in Seckel syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

Cep164, a novel centriole appendage protein required for primary cilium formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

Novel CENPJ mutation causes Seckel syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

1 reference

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21 March 2017

Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: the role of ninein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

21 March 2017

NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Opposing effects of pericentrin and microcephalin on the pericentriolar material regulate CHK1 activation in the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Spermitin: a novel mitochondrial protein in Drosophila spermatids

1 reference

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28 September 2017

Microtubules provide directional information for core PCP function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Small organelle, big responsibility: the role of centrosomes in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Centrosomes as signalling centres

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Pericentriolar material structure and dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Genomic analysis of primordial dwarfism reveals novel disease genes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Amorphous no more: subdiffraction view of the pericentriolar material architecture

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28 September 2017

Centrosome-dependent asymmetric inheritance of the midbody ring in Drosophila germline stem cell division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Establishment and mitotic characterization of new Drosophila acentriolar cell lines from DSas-4 mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

A protein complex network of Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

A primary microcephaly protein complex forms a ring around parental centrioles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Mechanisms and pathways of growth failure in primordial dwarfism.

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28 September 2017

Cdk5rap2 exposes the centrosomal root of microcephaly syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

The conversion of centrioles to centrosomes: essential coupling of duplication with segregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Assaying locomotor, learning, and memory deficits in Drosophila models of neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Drosophila neuroblasts retain the daughter centrosome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Centrioles: active players or passengers during mitosis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Centrocortin cooperates with centrosomin to organize Drosophila embryonic cleavage furrows

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Drosophila bld10 is a centriolar protein that regulates centriole, basal body, and motile cilium assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Proper recruitment of gamma-tubulin and D-TACC/Msps to embryonic Drosophila centrosomes requires Centrosomin Motif 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.

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28 September 2017

A role for a novel centrosome cycle in asymmetric cell division

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28 September 2017

Flies without centrioles

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28 September 2017

Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Reorganization of microtubule nucleation during muscle differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Dynamic analysis of larval locomotion in Drosophila chordotonal organ mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

An interaction type of genetic screen reveals a role of the Rab11 gene in oskar mRNA localization in the developing Drosophila melanogaster oocyte

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Centrosome-independent mitotic spindle formation in vertebrates

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28 September 2017

Spindle assembly and mitosis without centrosomes in parthenogenetic Sciara embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Drosophila centrosomin protein is required for male meiosis and assembly of the flagellar axoneme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Studies of microcephalic primordial dwarfism I: approach to a delineation of the Seckel syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

The Golgi apparatus remains associated with microtubule organizing centers during myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Organization of the cytoskeleton in early Drosophila embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Molecular characterization of bsg25D: a blastoderm-specific locus of Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

Microtubule polarities indicate that nucleation and capture of microtubules occurs at cell surfaces in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 September 2017

The centriolar protein Bld10/Cep135 is required to establish centrosome asymmetry in Drosophila neuroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

31 May 2018

Patronin regulates the microtubule network by protecting microtubule minus ends.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

31 May 2018

Apical/basal spindle orientation is required for neuroblast homeostasis and neuronal differentiation in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

31 May 2018

Asymmetric inheritance of mother versus daughter centrosome in stem cell division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

31 May 2018

RNAi in cultured Drosophila cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

31 May 2018

Comparative in vivo and in vitro genotoxicity studies of airborne particle extract in mice

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

BLD10/CEP135 is a microtubule-associated protein that controls the formation of the flagellum central microtubule pair

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

Centrosomes and mitotic spindle poles: a recent liaison?

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

Developmentally regulated elimination of damaged nuclei involves a Chk2-dependent mechanism of mRNA nuclear retention.

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

The centrosome-nucleus complex and microtubule organization in the Drosophila oocyte

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

Zygotic development without functional mitotic centrosomes.

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

Drosophila Cep135/Bld10 maintains proper centriole structure but is dispensable for cartwheel formation

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

Mutations in centrosomin reveal requirements for centrosomal function during early Drosophila embryogenesis.

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E15-09-0655

21 January 2018

The role of centrosomes and astral microtubules during asymmetric division of Drosophila neuroblasts.

1 reference

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28 November 2018

Genetically similar transduction mechanisms for touch and hearing in Drosophila.

1 reference

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28 November 2018

The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 November 2018

Nuclear-fallout, a Drosophila protein that cycles from the cytoplasm to the centrosomes, regulates cortical microfilament organization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4884065

28 November 2018

Hypersensitivity of Drosophila mei-41 mutants to hydroxyurea is associated with reduced mitotic chromosome stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/27053665

12 December 2020

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31 March 2020

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31 March 2020

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31 March 2020

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