Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors (Q27310950)

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English	Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors	scientific article

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Europe PubMed Central

PubMed publication ID

26 June 2017

Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors (English)

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Europe PubMed Central

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26 June 2017

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25900119%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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Jonathan Fischell

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10 June 2020

Adam M Van Dyke

2

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10 June 2020

Tara A LeGates

4

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10 June 2020

Scott M Thompson

5

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10 June 2020

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22 April 2015

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26 June 2017

Neuropsychopharmacology

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10 June 2020

40

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10 June 2020

11

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10 June 2020

2499-2509

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10 June 2020

Allostasis and allostatic load: implications for neuropsychopharmacology

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21 March 2017

Chronic stress induces a selective decrease in AMPA receptor-mediated synaptic excitation at hippocampal temporoammonic-CA1 synapses

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21 March 2017

The mesolimbic dopamine reward circuit in depression

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21 March 2017

Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

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21 March 2017

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

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7 April 2017

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

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7 April 2017

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

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7 April 2017

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28 September 2017

Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics

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28 September 2017

Restoring mood balance in depression: ketamine reverses deficit in dopamine-dependent synaptic plasticity

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28 September 2017

Neurobiology of stress, depression, and rapid acting antidepressants: remodeling synaptic connections

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28 September 2017

Ketamine alters oscillatory coupling in the hippocampus

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28 September 2017

The impact of NMDA receptor blockade on human working memory-related prefrontal function and connectivity

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28 September 2017

Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.

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Synaptic mechanisms underlying rapid antidepressant action of ketamine

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28 September 2017

Activation of mammalian target of rapamycin and synaptogenesis: role in the actions of rapid-acting antidepressants

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28 September 2017

Synaptic potentiation is critical for rapid antidepressant response to ketamine in treatment-resistant major depression

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28 September 2017

Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents

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28 September 2017

Comparison of the effects of acute and chronic administration of ketamine on hippocampal oscillations: relevance for the NMDA receptor hypofunction model of schizophrenia

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28 September 2017

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

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28 September 2017

Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure

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28 September 2017

Ketamine and the next generation of antidepressants with a rapid onset of action

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28 September 2017

GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus.

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28 September 2017

NMDA receptor-dependent switching between different gamma rhythm-generating microcircuits in entorhinal cortex.

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28 September 2017

RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors

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28 September 2017

NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons

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28 September 2017

Stress, depression, and neuroplasticity: a convergence of mechanisms

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28 September 2017

GABA(A) receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders

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28 September 2017

L-655,708 enhances cognition in rats but is not proconvulsant at a dose selective for alpha5-containing GABAA receptors.

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28 September 2017

Synaptic and nonsynaptic localization of GABAA receptors containing the alpha5 subunit in the rat brain

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28 September 2017

Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors

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28 September 2017

Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268.

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28 September 2017

[3H]L-655,708, a novel ligand selective for the benzodiazepine site of GABAA receptors which contain the alpha 5 subunit

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28 September 2017

GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits

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28 September 2017

Heightened synaptic plasticity of hippocampal CA1 neurons during a cholinergically induced rhythmic state

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28 September 2017

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

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28 September 2017

Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens.

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Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex.

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31 May 2018

Specific subtypes of GABAA receptors mediate phasic and tonic forms of inhibition in hippocampal pyramidal neurons.

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31 May 2018

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31 May 2018

Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex

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31 May 2018

Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant

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31 May 2018

Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons

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31 May 2018

In vivo labelling of alpha5 subunit-containing GABA(A) receptors using the selective radioligand [(3)H]L-655,708.

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21 January 2018

In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist.

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21 January 2018

What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression

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21 January 2018

Modulation of septo-hippocampal Theta activity by GABAA receptors: an experimental and computational approach

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21 January 2018

Differential effects produced by ketamine on oscillatory activity recorded in the rat hippocampus, dorsal striatum and nucleus accumbens

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21 January 2018

Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors

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21 January 2018

Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade

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21 January 2018

Strain differences in sucrose preference and in the consequences of unpredictable chronic mild stress

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21 January 2018

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

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21 January 2018

Citalopram counteracts depressive-like symptoms evoked by chronic social stress in rats

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21 January 2018

Alpha 5 subunit-containing GABAA receptors affect the dynamic range of mouse hippocampal kainate-induced gamma frequency oscillations in vitro.

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21 January 2018

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The glutamate synapse in neuropsychiatric disorders. Focus on schizophrenia and Alzheimer's disease

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28 November 2018

α5GABAA Receptors Regulate the Intrinsic Excitability of Mouse Hippocampal Pyramidal Neurons

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31 March 2020

Expression of GABA(A) receptor alpha5 subunit-like immunoreactivity in human hippocampus

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Identifiers

10.1038/NPP.2015.112

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25900119%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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0 references

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25900119%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25900119%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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