Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth (Q27320013)

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22 February 2020

title

Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth (English)

1 reference

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Mechanistic target of rapamycin kinase

22 February 2020

main subject

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GOA release 2020-03-11

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7

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22 February 2020

George Thomas

10

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22 February 2020

E. Dale Abel

12

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22 February 2020

author name string

Yi Zhu

1

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22 February 2020

Karla M P Pires

2

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22 February 2020

Kevin J Whitehead

3

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22 February 2020

Curtis D Olsen

4

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22 February 2020

Benjamin Wayment

5

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22 February 2020

Yi Cheng Zhang

6

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22 February 2020

Olesya Ilkun

8

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22 February 2020

Sheldon E Litwin

9

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22 February 2020

Sara C Kozma

11

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22 February 2020

language of work or name

English

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publication date

14 January 2013

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22 February 2020

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22 February 2020

volume

8

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22 February 2020

issue

1

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22 February 2020

page(s)

e54221

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Creative Commons Attribution 4.0 International

22 February 2020

copyright license

start time

14 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

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Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

21 March 2017

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

21 March 2017

1 reference

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

21 March 2017

1 reference

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Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis

21 March 2017

1 reference

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FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse

21 March 2017

1 reference

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mTOR signaling at a glance

21 March 2017

1 reference

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mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

7 April 2017

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Animal research: reporting in vivo experiments--the ARRIVE guidelines

7 April 2017

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Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.

28 September 2017

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MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

28 September 2017

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Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

28 September 2017

1 reference

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TOR complex 2: a signaling pathway of its own.

28 September 2017

1 reference

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mTOR complex 2 in adipose tissue negatively controls whole-body growth

28 September 2017

1 reference

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Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms.

28 September 2017

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The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

28 September 2017

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Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy

28 September 2017

1 reference

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Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function

28 September 2017

1 reference

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A chemical method for fast and sensitive detection of DNA synthesis in vivo

28 September 2017

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Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

28 September 2017

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Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3

28 September 2017

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28 September 2017

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Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

28 September 2017

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31 May 2018

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Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling

28 November 2018

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Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure

28 November 2018

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Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition

28 November 2018

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Codon optimization markedly improves doxycycline regulated gene expression in the mouse heart

28 November 2018

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10.1371/JOURNAL.PONE.0054221

28 November 2018

Identifiers

DOI

2 references

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22 February 2020

ADS bibcode

2013PLoSO...854221Z

0 references

1 reference

2 references

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22 February 2020

PubMed publication ID

23342106

2 references

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