Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees (Q27489101)

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English	Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees	scientific article

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scholarly article

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Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees (English)

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Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

J Bukh

7

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Suzanne U. Emerson

4

object named as

S U Emerson

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Robert H. Purcell

5

object named as

R H Purcell

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Sugantha Govindarajan

3

object named as

S Govindarajan

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author name string

X Forns

1

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R Thimme

2

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F V Chisari

6

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language of work or name

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publication date

21 November 2000

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Proceedings of the National Academy of Sciences of the United States of America

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97

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24

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13318-23

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Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

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20 March 2017

Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81.

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20 March 2017

Acute hepatitis C virus structural gene sequences as predictors of persistent viremia: hypervariable region 1 as a decoy

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20 March 2017

In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone

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20 March 2017

Binding of hepatitis C virus to CD81

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20 March 2017

Towards a solution for hepatitis C virus hypervariability: mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large number of viral variants

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27222

20 March 2017

Long-term evolution of the hypervariable region of hepatitis C virus in a common-source-infected cohort.

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20 March 2017

Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

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20 March 2017

Epitope mapping of antibodies directed against hypervariable region 1 in acute self-limiting and chronic infections due to hepatitis C virus

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20 March 2017

Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein

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20 March 2017

Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus

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20 March 2017

Analysis of successful immune responses in persons infected with hepatitis C virus

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20 March 2017

Transmission of Hepatitis C by Intrahepatic Inoculation with Transcribed RNA

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20 March 2017

The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies

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7 April 2017

Analysis of a successful immune response against hepatitis C virus

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7 April 2017

A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells

2 references

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7 April 2017

https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response

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7 April 2017

Genetic Heterogeneity of Hepatitis C Virus: Quasispecies and Genotypes

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7 April 2017

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

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7 April 2017

Nucleotide sequence and mutation rate of the H strain of hepatitis C virus

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7 April 2017

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins

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7 April 2017

Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections

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7 April 2017

Evolution of the hypervariable region of hepatitis C virus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27222

29 September 2017

Quasispecies in viral persistence and pathogenesis of hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27222

29 September 2017

Hypervariable region 1 variants act as TCR antagonists for hepatitis C virus-specific CD4+ T cells.

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29 September 2017

Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity

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29 September 2017

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

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29 September 2017

Early antibody response against hypervariable region 1 is associated with acute self-limiting infections of hepatitis C virus.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27222

29 September 2017

Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions

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29 September 2017

Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif

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29 September 2017

Hypervariable regions in the putative glycoprotein of hepatitis C virus

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29 September 2017

Experimental infection of chimpanzees with hepatitis C virus of genotype 5a: genetic analysis of the virus and generation of a standardized challenge pool

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2 June 2018

Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.

1 reference

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2 June 2018

HIV entry and tropism: the chemokine receptor connection.

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2 June 2018

The quasispecies of hepatitis C virus and the host immune response

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2 June 2018

Impaired induction of cytotoxic T lymphocytes by antagonism of a weak agonist borne by a variant hepatitis C virus epitope

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2 June 2018

Hepatitis C virus-specific CTL responses in the liver of chimpanzees with acute and chronic hepatitis C.

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2 June 2018

A structurally flexible and antigenically variable N-terminal domain of the hepatitis C virus E2/NS1 protein: implication for an escape from antibody.

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2 June 2018

A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures

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https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Antibodies in human sera specific to hypervariable region 1 of hepatitis C virus can block viral attachment

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https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Patients infected with the same hepatitis C virus strain display different kinetics of the isolate-specific antibody response.

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21 January 2018

Medical cardiovascular treatment trials: Relevant to medical ophthalmology in 1997?

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21 January 2018

Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras

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https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Characterization of modified hepatitis C virus E2 proteins expressed on the cell surface.

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https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Growth hormone induces CCAAT/enhancer binding protein alpha (C/EBPalpha) in cultured rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Association of hepatitis C virus-specific CD8+ T cells with viral clearance in acute hepatitis C.

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https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

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https://api.crossref.org/works/10.1073%2FPNAS.230453597

21 January 2018

Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV.

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27 November 2018

National Institutes of Health Consensus Development Conference Panel statement: management of hepatitis C

1 reference

https://pubmed.ncbi.nlm.nih.gov/11078521

12 December 2020

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10.1073/PNAS.230453597

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2000PNAS...9713318F

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release_jaldccmhunc4ndiby6i5mgtfle

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