Exosome non-catalytic core subunit CSL4 YNL232W (Q27547367)

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fungal protein found in Saccharomyces cerevisiae S288c

• CSL4
• exosome non-catalytic core subunit CSL4
• YNL232W

edit

Language	Label	Description	Also known as
English	Exosome non-catalytic core subunit CSL4 YNL232W	fungal protein found in Saccharomyces cerevisiae S288c	CSL4 exosome non-catalytic core subunit CSL4 YNL232W

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P53859

subclass of

protein

1 reference

stated in

UniProt

retrieved

19 January 2017

UniProt protein ID

P53859

found in taxon

Saccharomyces cerevisiae S288c

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P53859

encoded by

CSL4

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P53859

molecular function

RNA binding

determination method

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P53859

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

protein binding

determination method

IPI

10 references

retrieved

9 May 2019

stated in

Subunit architecture of multimeric complexes isolated directly from cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

An in vivo map of the yeast protein interactome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

Structure of an Rrp6–RNA exosome complex bound to poly(A) RNA

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

RNA channelling by the eukaryotic exosome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

Proteome survey reveals modularity of the yeast cell machinery

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

RNA degradation paths in a 12-subunit nuclear exosome complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

retrieved

9 May 2019

stated in

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IPI

molecular function

determination method

ND

1 reference

retrieved

9 May 2019

stated in

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

ND

cell component

nucleolus

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P53859

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

cytoplasmic exosome (RNase complex)

determination method

IDA

2 references

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

retrieved

9 May 2019

stated in

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

exosome (RNase complex)

determination method

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P53859

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

nuclear exosome (RNase complex)

determination method

IDA

2 references

retrieved

21 June 2018

stated in

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53859&geneProductId=UniProtKB:P53859

determination method

IDA

retrieved

21 June 2018

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53859&geneProductId=UniProtKB:P53859

determination method

IDA

cytoplasm

determination method

IDA

IEA

2 references

retrieved

21 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P53859

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53859&geneProductId=UniProtKB:P53859

determination method

IEA

retrieved

21 June 2018

stated in

Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53859&geneProductId=UniProtKB:P53859

determination method

IDA

nucleus

determination method

IDA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P53859

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

retrieved

9 May 2019

stated in

Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

nuclear exosome (RNase complex)

determination method

IBA

IDA

3 references

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

retrieved

9 May 2019

stated in

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IBA

cytoplasm

determination method

IBA

IDA

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P53859

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

retrieved

9 May 2019

stated in

Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IBA

biological process

nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay

determination method

IC

1 reference

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IC

nuclear-transcribed mRNA catabolic process, non-stop decay

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Exosome-mediated recognition and degradation of mRNAs lacking a termination codon

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IMP

polyadenylation-dependent snoRNA 3'-end processing

determination method

IC

1 reference

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IC

nuclear polyadenylation-dependent tRNA catabolic process

determination method

IDA

3 references

retrieved

9 May 2019

stated in

A new yeast poly(A) polymerase complex involved in RNA quality control

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

retrieved

9 May 2019

stated in

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

retrieved

9 May 2019

stated in

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IDA

nonfunctional rRNA decay

determination method

IC

1 reference

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IC

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

determination method

IMP

2 references

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IMP

retrieved

9 May 2019

stated in

Functions of the exosome in rRNA, snoRNA and snRNA synthesis

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IMP

nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'

determination method

IMP

IGI

4 references

retrieved

9 May 2019

stated in

Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IMP

retrieved

9 May 2019

stated in

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IMP

retrieved

9 May 2019

stated in

Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IGI

retrieved

9 May 2019

stated in

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IGI

nuclear polyadenylation-dependent rRNA catabolic process

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IMP

nuclear polyadenylation-dependent mRNA catabolic process

determination method

IC

1 reference

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IC

rRNA processing

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P53859

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

ncRNA 3'-end processing

determination method

IC

1 reference

retrieved

9 May 2019

stated in

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IC

poly(A)+ mRNA export from nucleus

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IMP

RNA processing

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53859

determination method

IEA

Identifiers

RefSeq protein ID

NP_014167

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

855489

UniProt protein ID

P53859

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P53859

Ensembl protein ID

YNL232W

1 reference

stated in

ensembl Release 106

Ensembl protein ID

YNL232W

Saccharomyces Genome Database ID

S000005176

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

855489

 

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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