DNA topoisomerase 2 YNL088W (Q27547626)

DNA topoisomerase, type IIA-like domain superfamily

1 reference

Ribosomal protein S5 domain 2-type fold

1 reference

DNA topoisomerase, type IIA, subunit B, C-terminal

1 reference

DNA topoisomerase II, eukaryotic-type

1 reference

Ribosomal protein S5 domain 2-type fold, subgroup

1 reference

C-terminal associated domain of TOPRIM, protein family

1 reference

DNA topoisomerase, type IIA, subunit B, domain 2, protein family

1 reference

DNA topoisomerase 2, TOPRIM domain, protein family

1 reference

DNA topoisomerase, type IIA, subunit A/C-terminal domain, protein family

1 reference

Histidine kinase/HSP90-like ATPase family

1 reference

TOPRIM domain, protein family

1 reference

DNA topoisomerase, type IIA, conserved site, protein family

1 reference

Saccharomyces cerevisiae S288c

found in taxon

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

1 reference

9 May 2019

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

3 references

9 May 2019

9 May 2019

Yeast DNA topoisomerase II is encoded by a single-copy, essential gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

9 May 2019

The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

DNA topoisomerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

1 reference

9 May 2019

isomerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

1 reference

9 May 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

1 reference

9 May 2019

protein binding

1 reference

9 May 2019

The identification of a functional interaction between PKC and topoisomerase II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

identical protein binding

4 references

9 May 2019

Structure of a topoisomerase II–DNA–nucleotide complex reveals a new control mechanism for ATPase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

9 May 2019

Structural basis for gate-DNA recognition and bending by type IIA topoisomerases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

9 May 2019

A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

9 May 2019

Structure and mechanism of DNA topoisomerase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

1 reference

14 February 2019

cell component

synaptonemal complex

1 reference

9 May 2019

Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

DNA replication termination region

1 reference

9 May 2019

Replication termination at eukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786

3 references

10 September 2018

10 September 2018

The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

4 references

9 May 2019

9 May 2019

The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

9 May 2019

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

HDA

mitochondrion

HDA

1 reference

9 May 2019

Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

replication fork progression beyond termination site

HDA

biological process

1 reference

9 May 2019

Replication termination at eukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

chromatin remodeling at centromere

1 reference

9 May 2019

DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

sister chromatid segregation

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

resolution of meiotic recombination intermediates

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

DNA strand elongation involved in DNA replication

1 reference

9 May 2019

Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

reciprocal meiotic recombination

1 reference

9 May 2019

Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

regulation of mitotic recombination

1 reference

9 May 2019

Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786

mitotic DNA integrity checkpoint signaling

1 reference

27 March 2018

A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin.

Saccharomyces Genome Database ID

SGD

S000005032

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786

mitotic DNA integrity checkpoint signaling

DNA topoisomerase, type IIA, subunit A/C-terminal

has part(s)

1 reference

TOPRIM domain

1 reference

C-terminal associated domain of TOPRIM

1 reference

DNA topoisomerase, type IIA, subunit B, domain 2

1 reference

DNA topoisomerase, type IIA, conserved site

1 reference

Histidine kinase/HSP90-like ATPase domain

1 reference

DNA topoisomerase 2, TOPRIM domain

1 reference