Multifunctional nuclease RAD27 YKL113C (Q27547885)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26793

5'-3' exonuclease, C-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26793

Flap endonuclease 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26793

XPG N-terminal domain, protein family

1 reference

XPG-I domain, protein family

1 reference

XPG conserved site, protein family

1 reference

Helix-hairpin-helix motif, class 2, protein family

1 reference

Saccharomyces cerevisiae S288c

found in taxon

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

hydrolase activity, acting on ester bonds

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

exonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

endonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

protein binding

4 references

9 May 2019

Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

5'-3' exonuclease activity

1 reference

5 June 2018

Purification and characterization of the DNA polymerase alpha associated exonuclease: the RTH1 gene product

SGD

S000001596

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

5'-flap endonuclease activity

1 reference

5 June 2018

Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate

SGD

S000001596

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

magnesium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

5'-flap endonuclease activity

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

10 September 2018

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

crossover junction endodeoxyribonuclease activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

5'-flap endonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

3 references

9 May 2019

9 May 2019

Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

single-stranded DNA 5'-3' exodeoxyribonuclease activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

flap endonuclease activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

double-stranded DNA 5'-3' exodeoxyribonuclease activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

5'-3' exonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

3 references

9 May 2019

9 May 2019

Purification and characterization of the DNA polymerase alpha associated exonuclease: the RTH1 gene product

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

cell component

nucleolus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

3 references

10 September 2018

10 September 2018

Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

10 September 2018

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

cytosol

1 reference

9 May 2019

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

4 references

1 January 2018

1 January 2018

Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

1 January 2018

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

1 January 2018

Global analysis of protein localization in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

HDA

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

5 references

9 May 2019

9 May 2019

Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

9 May 2019

Global analysis of protein localization in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

HDA

cytoplasm

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

maintenance of DNA trinucleotide repeats

biological process

IMP

IGI

2 references

DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

double-strand break repair via nonhomologous end joining

1 reference

9 May 2019

Processing and joining of DNA ends coordinated by interactions among Dnl4/Lif1, Pol4, and FEN-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

nucleic acid phosphodiester bond hydrolysis

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

DNA replication, removal of RNA primer

1 reference

5 June 2018

Reconstituted Okazaki fragment processing indicates two pathways of primer removal

SGD

S000001596

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

base-excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

1 reference

9 May 2019

maintenance of DNA trinucleotide repeats

Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeast

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

IMP

1 January 2018

Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

IGI

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

DNA replication, removal of RNA primer

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

3 references

1 January 2018

1 January 2018

Reconstituted Okazaki fragment processing indicates two pathways of primer removal

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

UV-damage excision repair

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26793

removal of RNA primer involved in mitotic DNA replication

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26793&geneProductId=UniProtKB:P26793

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference