8-oxoguanine glycosylase OGG1 YML060W (Q27548010)

8-oxoguanine DNA-glycosylase

1 reference

Helix-turn-helix, base-excision DNA repair, C-terminal

1 reference

8-oxoguanine DNA glycosylase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

HhH-GPD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

oxidized purine nucleobase lesion DNA N-glycosylase activity

lyase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

1 reference

21 June 2018

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

hydrolase activity, acting on glycosyl bonds

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

damaged DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

protein binding

IPI

1 reference

21 June 2018

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

oxidized purine nucleobase lesion DNA N-glycosylase activity

IPI

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

3 references

10 September 2018

10 September 2018

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

DNA N-glycosylase activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

oxidized purine DNA binding

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

cell component

mitochondrion

1 reference

14 February 2019

Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

CBF3 complex

1 reference

14 February 2019

Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

3 references

14 February 2019

14 February 2019

Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

biological process

DNA repair

Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

14 February 2019

base-excision repair, AP site formation

1 reference

21 June 2018

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53397&geneProductId=UniProtKB:P53397

error-free translesion synthesis

IGI

1 reference

14 February 2019

PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

telomere maintenance via telomerase

IGI

IMP

1 reference

14 February 2019

Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

IMP

metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

nucleotide-excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

base-excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

1 reference

14 February 2019

base-excision repair, AP site formation

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53397

telomere maintenance via telomerase

8-oxoguanine DNA glycosylase, N-terminal

IMP

has part(s)

1 reference

HhH-GPD domain

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference