Proliferating cell nuclear antigen YBR088C (Q27550140)

Proliferating cell nuclear antigen, PCNA, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Proliferating cell nuclear antigen, PCNA, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Proliferating cell nuclear antigen, PCNA, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

DNA polymerase processivity factor activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

3 references

27 February 2018

27 February 2018

DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

protein binding

12 references

9 May 2019

Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interaction with PCNA is essential for yeast DNA polymerase eta function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Defining the budding yeast chromatin-associated interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

identical protein binding

6 references

9 May 2019

Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interaction with PCNA is essential for yeast DNA polymerase eta function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

The structure of a ring-opened proliferating cell nuclear antigen-replication factor C complex revealed by fluorescence energy transfer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

DNA polymerase processivity factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

4 references

9 May 2019

9 May 2019

DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

cell component

PCNA complex

1 reference

27 February 2018

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

replication fork

1 reference

9 May 2019

The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

telomere

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

3 references

9 May 2019

9 May 2019

Localization of proteins that are coordinately expressed with Cln2 during the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

silent mating-type cassette heterochromatin assembly

biological process

DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

1 reference

9 May 2019

postreplication repair

DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

1 reference

9 May 2019

regulation of DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

1 reference

9 May 2019

maintenance of DNA trinucleotide repeats

Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeast

2 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

positive regulation of exodeoxyribonuclease activity

1 reference

9 May 2019

Stimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

mitotic sister chromatid cohesion

leading strand elongation

1 reference

27 February 2018

Saccharomyces cerevisiae replication factor C. I. Purification and characterization of its ATPase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands

1 reference

9 May 2019

Stimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

error-free translesion synthesis

1 reference

9 May 2019

PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

establishment of mitotic sister chromatid cohesion

1 reference

9 May 2019

PCNA controls establishment of sister chromatid cohesion during S phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

lagging strand elongation

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

2 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

mitotic cell cycle

1 reference

9 May 2019

Proliferating cell nuclear antigen (pol30) mutations suppress cdc44 mutations and identify potential regions of interaction between the two encoded proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

meiotic mismatch repair

Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast

2 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

DNA mismatch repair

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

4 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

nucleotide-excision repair

1 reference

9 May 2019

The N-degron protein degradation strategy for investigating the function of essential genes: requirement for replication protein A and proliferating cell nuclear antigen proteins for nucleotide excision repair in yeast extracts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

1 reference

9 May 2019

leading strand elongation

DNA mismatch repair

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

translesion synthesis

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

Proliferating cell nuclear antigen, PCNA, conserved site

has part(s)

1 reference

Proliferating cell nuclear antigen, PCNA, N-terminal

1 reference

Proliferating cell nuclear antigen, PCNA, C-terminal

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference