Proteasome core particle subunit alpha 4 YOL038W (Q27550674)

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fungal protein found in Saccharomyces cerevisiae S288c

• PRE6
• proteasome core particle subunit alpha 4
• YOL038W

edit

Language	Label	Description	Also known as
English	Proteasome core particle subunit alpha 4 YOL038W	fungal protein found in Saccharomyces cerevisiae S288c	PRE6 proteasome core particle subunit alpha 4 YOL038W

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P40303

subclass of

protein

1 reference

stated in

UniProt

retrieved

19 January 2017

UniProt protein ID

P40303

part of

Nucleophile aminohydrolases, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P40303

Proteasome alpha-subunit, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Proteasome beta-type subunit, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P40303

encoded by

PRE6

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P40303

molecular function

hydrolase activity

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

threonine-type endopeptidase activity

determination method or standard

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

peptidase activity

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

endopeptidase activity

determination method or standard

IEA

1 reference

retrieved

5 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IEA

protein binding

determination method or standard

IPI

8 references

retrieved

9 May 2019

stated in

beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

9 May 2019

stated in

Regulation of nuclear proteasome by Rhp6/Ubc2 through ubiquitination and destruction of the sensor and anchor Cut8.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

9 May 2019

stated in

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

9 May 2019

stated in

A multimeric assembly factor controls the formation of alternative 20S proteasomes

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

9 May 2019

stated in

Structure-templated predictions of novel protein interactions from sequence information

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

9 May 2019

stated in

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

9 May 2019

stated in

Proteome survey reveals modularity of the yeast cell machinery

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

9 May 2019

stated in

Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IPI

molecular function

determination method or standard

ND

1 reference

retrieved

9 May 2019

stated in

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

ND

identical protein binding

determination method or standard

IPI

2 references

retrieved

5 June 2018

stated in

A multimeric assembly factor controls the formation of alternative 20S proteasomes

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IPI

retrieved

5 June 2018

stated in

High-definition macromolecular composition of yeast RNA-processing complexes

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IPI

endopeptidase activity

determination method or standard

IBA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

cell component

proteasome complex

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

nuclear outer membrane-endoplasmic reticulum membrane network

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

nucleus

determination method or standard

IEA

IDA

2 references

retrieved

5 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

5 June 2018

stated in

Reversible cytoplasmic localization of the proteasome in quiescent yeast cells.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IDA

proteasome storage granule

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

Reversible cytoplasmic localization of the proteasome in quiescent yeast cells.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

mitochondrion

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

proteasome core complex, alpha-subunit complex

determination method or standard

IEA

IDA

2 references

retrieved

5 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

5 June 2018

stated in

Structure of 20S proteasome from yeast at 2.4 A resolution

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IDA

cytoplasm

determination method or standard

IEA

1 reference

retrieved

5 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IEA

proteasome core complex

determination method or standard

IEA

1 reference

retrieved

5 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IEA

nucleus

determination method or standard

IBA

IDA

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

9 May 2019

stated in

Reversible cytoplasmic localization of the proteasome in quiescent yeast cells.

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

cytoplasm

determination method or standard

IBA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

proteasome core complex

determination method or standard

IBA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

proteasome core complex, alpha-subunit complex

determination method or standard

IBA

IDA

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

retrieved

9 May 2019

stated in

Structure of 20S proteasome from yeast at 2.4 A resolution

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

biological process

proteolysis involved in cellular protein catabolic process

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

proteolysis

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P40303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

ubiquitin-dependent protein catabolic process

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IEA

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method or standard

IDA

2 references

retrieved

5 June 2018

stated in

Substrate selection by the proteasome during degradation of protein complexes

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IDA

retrieved

5 June 2018

stated in

Selective degradation of ubiquitinated Sic1 by purified 26S proteasome yields active S phase cyclin-Cdk

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IDA

proteasomal ubiquitin-independent protein catabolic process

determination method or standard

IDA

1 reference

retrieved

5 June 2018

stated in

Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40303&geneProductId=UniProtKB:P40303

determination method or standard

IDA

proteasomal protein catabolic process

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

proteasomal ubiquitin-independent protein catabolic process

determination method or standard

IBA

IDA

2 references

retrieved

9 May 2019

stated in

Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method or standard

IBA

IDA

3 references

retrieved

9 May 2019

stated in

Substrate selection by the proteasome during degradation of protein complexes

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

retrieved

9 May 2019

stated in

Selective degradation of ubiquitinated Sic1 by purified 26S proteasome yields active S phase cyclin-Cdk

GOA

curator

SGD

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40303

determination method or standard

IBA

has part(s)

Proteasome alpha-subunit, N-terminal domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P40303

Proteasome beta-type subunit, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P40303

Identifiers

RefSeq protein ID

NP_014604

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

854119

UniProt protein ID

P40303

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P40303

Ensembl protein ID

YOL038W

1 reference

stated in

ensembl Release 106

Ensembl protein ID

YOL038W

Saccharomyces Genome Database ID

S000005398

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

854119

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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