Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition (Q27647015)

https://api.crossref.org/works/10.1074%2FJBC.M704587200

The complement system in regulation of adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Complement inhibitors: a resurgent concept in anti-inflammatory therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Drug design using the example of the complement system inhibitors' development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Solution structure of Compstatin, a potent complement inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

C3 activation is inhibited by analogs of compstatin but not by serine protease inhibitors or peptidyl alpha-ketoheterocycles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Studies of structure-activity relations of complement inhibitor compstatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Structures of complement component C3 provide insights into the function and evolution of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Structure of C3b reveals conformational changes that underlie complement activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

The structure of bovine complement component 3 reveals the basis for thioester function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Structural transitions of complement component C3 and its activation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Isolation of a fragment (C3a) of the third component of human complement containing anaphylatoxin and chemotactic activity and description of an anaphylatoxin inactivator of human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Likelihood-enhanced fast translation functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Use of non-crystallographic symmetry in protein structure refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Structural insights into the central complement component C3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

A structural basis for complement inhibition by Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Inhibition of Heparin/Protamine Complex-Induced Complement Activation by Compstatin in Baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200

Hydrophobic Effect and Hydrogen Bonds Account for the Improved Activity of a Complement Inhibitor, Compstatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704587200