Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII) (Q27678322)

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English	Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII)	scientific article

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1 March 2020

Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII) (English)

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1 March 2020

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endoplasmic reticulum

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2

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1 March 2020

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Chunlei Zheng

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1 March 2020

Vaijayanti Das

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1 March 2020

Jay C Nix

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1 March 2020

Edvard Wigren

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1 March 2020

Bin Zhang

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24 May 2013

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1 March 2020

Journal of Biological Chemistry

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1 March 2020

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28

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1 March 2020

20499-20509

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1 March 2020

Receptor-mediated ER export of human MHC class I molecules is regulated by the C-terminal single amino acid

1 reference

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Role of the lectin VIP36 in post-ER quality control of human alpha1-antitrypsin

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20 March 2017

Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII

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Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor

1 reference

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20 March 2017

The crystal structure of the carbohydrate-recognition domain of the glycoprotein sorting receptor p58/ERGIC-53 reveals an unpredicted metal-binding site and conformational changes associated with calcium ion binding

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20 March 2017

Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711315

20 March 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

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20 March 2017

Features and development of Coot

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20 March 2017

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20 March 2017

Scaling and assessment of data quality

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Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex

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ERGIC-53 and traffic in the secretory pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711315

20 March 2017

LMAN1 and MCFD2 form a cargo receptor complex and interact with coagulation factor VIII in the early secretory pathway

1 reference

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1 reference

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Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711315

29 September 2017

Vesicular calcium regulates coat retention, fusogenicity, and size of pre-Golgi intermediates.

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29 September 2017

EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII.

1 reference

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Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin

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29 September 2017

The sugar-binding ability of ERGIC-53 is enhanced by its interaction with MCFD2.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711315

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Cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex

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Carbohydrate- and conformation-dependent cargo capture for ER-exit

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Reconstitution of COPII vesicle fusion to generate a pre-Golgi intermediate compartment

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LMAN1 is a molecular chaperone for the secretion of coagulation factor VIII.

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10.1074/JBC.M113.461434

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