The Crystal Structure of Human Argonaute2 (Q27678770)

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Language	Label	Description	Also known as
English	The Crystal Structure of Human Argonaute2	scientific article

Statements

instance of

scholarly article

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title

The Crystal Structure of Human Argonaute2 (English)

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main subject

crystal structure

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author name string

Nicole T Schirle

series ordinal

1

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Ian J MacRae

series ordinal

2

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language of work or name

English

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publication date

25 May 2012

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published in

Science

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volume

336

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issue

6084

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page(s)

1037-40

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cites work

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

MicroRNAs: target recognition and regulatory functions

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Structure of the guide-strand-containing argonaute silencing complex

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Structure and conserved RNA binding of the PAZ domain

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

REFMAC5 for the refinement of macromolecular crystal structures

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

XDS

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Coot: model-building tools for molecular graphics

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Argonaute2 is the catalytic engine of mammalian RNAi

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

MicroRNAs: genomics, biogenesis, mechanism, and function

2 references

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1126%2FSCIENCE.1221551

retrieved

22 April 2017

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

20 March 2017

Crystal structure of Argonaute and its implications for RISC slicer activity

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

7 April 2017

Purification and assembly of human Argonaute, Dicer, and TRBP complexes

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

Functional dissection of the human TNRC6 (GW182-related) family of proteins

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

Reciprocal-space solvent flattening

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

29 September 2017

A C-terminal silencing domain in GW182 is essential for miRNA function

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

2 June 2018

siRNA function in RNAi: a chemical modification analysis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

2 June 2018

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521581

retrieved

27 November 2018

Identifiers

DOI

10.1126/SCIENCE.1221551

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

631473

ADS bibcode

2012Sci...336.1037S

0 references

OpenCitations bibliographic resource ID

631473

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

631473

PMC publication ID

3521581

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

631473

PubMed publication ID

22539551

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

631473

ResearchGate publication ID

224855876

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