Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation (Q27678948)

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Language	Label	Description	Also known as
English	Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation	scientific article

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instance of

scholarly article

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title

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation (English)

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main subject

catalysis

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author

Stephen W. Fesik

series ordinal

9

object named as

Stephen W Fesik

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author name string

Qi Sun

series ordinal

1

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Jason P Burke

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2

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Jason Phan

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3

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Michael C Burns

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4

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Edward T Olejniczak

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5

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Alex G Waterson

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6

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Taekyu Lee

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7

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Olivia W Rossanese

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8

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language of work or name

English

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publication date

18 June 2012

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published in

Angewandte Chemie International Edition

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volume

51

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issue

25

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page(s)

6140-3

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cites work

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The structural basis of the activation of Ras by Sos

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KRAS mutations in non-small cell lung cancer

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PubMed Central

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ras oncogenes in human cancer: a review

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

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7 April 2017

Discovering high-affinity ligands for proteins: SAR by NMR

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7 April 2017

An orthosteric inhibitor of the Ras-Sos interaction

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29 September 2017

Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer

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Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras

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29 September 2017

Fragment-based screening using X-ray crystallography and NMR spectroscopy

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A decade of fragment-based drug design: strategic advances and lessons learned

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Essential role for oncogenic Ras in tumour maintenance

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Molecular switch in signal transduction: reaction paths of the conformational changes in ras p21.

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29 September 2017

Activating KRAS mutations and overexpression of epidermal growth factor receptor as independent predictors in metastatic colorectal cancer patients treated with cetuximab

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21 January 2018

Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers

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reference URL

https://pubmed.ncbi.nlm.nih.gov/22566140

retrieved

12 December 2020

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Identifiers

DOI

10.1002/ANIE.201201358

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1626807

OpenCitations bibliographic resource ID

1626807

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1626807

PMC publication ID

3620661

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1626807

PubMed publication ID

22566140

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1626807

 

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