Why there are two cyclooxygenase isozymes (Q27863307)

PubMed publication ID

15 November 2016

1 reference

Europe PubMed Central

title

Why there are two cyclooxygenase isozymes (English)

1 reference

Journal of Clinical Investigation

PubMed publication ID

15 November 2016

W L Smith

1

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R Langenbach

series ordinal

2

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language of work or name

English

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publication date

June 2001

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published in

1 reference

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

volume

107

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issue

12

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page(s)

1491-5

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=200199

Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways

20 March 2017

1 reference

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Regulated formation of eicosanoids

20 March 2017

1 reference

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Arachidonic acid as a bioactive molecule

20 March 2017

1 reference

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Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice

20 March 2017

1 reference

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Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

20 March 2017

1 reference

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Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta

20 March 2017

1 reference

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Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid

20 March 2017

1 reference

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Cyclooxygenases: structural, cellular, and molecular biology

20 March 2017

1 reference

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Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2.

7 April 2017

1 reference

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Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.

29 September 2017

1 reference

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Distribution and function of prostanoid receptors: studies from knockout mice

29 September 2017

1 reference

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Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development

29 September 2017

1 reference

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Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways

29 September 2017

1 reference

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Opposing actions of prostaglandins and oxytocin determine the onset of murine labor

29 September 2017

1 reference

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Self-promotion? Intimate connections between APC and prostaglandin H synthase-2.

29 September 2017

1 reference

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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

29 September 2017

1 reference

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Identification of a third pathway for arachidonic acid mobilization and prostaglandin production in activated P388D1 macrophage-like cells

29 September 2017

1 reference

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Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity

2 June 2018

1 reference

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Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy

2 June 2018

1 reference

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Different substrate utilization between prostaglandin endoperoxide H synthase-1 and -2 in NIH3T3 fibroblasts

2 June 2018

1 reference

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Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice

2 June 2018

1 reference

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Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

2 June 2018

1 reference

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Disruption of cyclooxygenase-1 gene results in an impaired response to radiation injury.

2 June 2018

1 reference

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Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism.

27 November 2018

1 reference

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Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development.

27 November 2018

1 reference

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Multiple female reproductive failures in cyclooxygenase 2-deficient mice.

27 November 2018

1 reference

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Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

27 November 2018

1 reference

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Role of cyclooxygenase-2 in the healing of gastric ulcers in rats

27 November 2018

1 reference

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Prevention of myocardial infarction and stroke by aspirin: different mechanisms? Different dosage?

1 reference

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Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta

1 reference

12 December 2020

Inducible cyclooxygenase may have anti-inflammatory properties

1 reference

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Hydroperoxide dependence and cooperative cyclooxygenase kinetics in prostaglandin H synthase-1 and -2

1 reference

12 December 2020

Exogenously added human group X secreted phospholipase A(2) but not the group IB, IIA, and V enzymes efficiently release arachidonic acid from adherent mammalian cells

1 reference

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Inhibition of cyclooxygenase-2 prevents inflammation-mediated preterm labor in the mouse

1 reference

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Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation

1 reference

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NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2

1 reference

12 December 2020

Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases

1 reference

12 December 2020