Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy (Q27863360)

PubMed

PubMed publication ID

17549067

15 November 2016

title

Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy (English)

1 reference

PubMed

PubMed publication ID

15 November 2016

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A Ruzzo

1

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F Graziano

2

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F Loupakis

3

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D Santini

4

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V Catalano

5

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R Bisonni

6

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R Ficarelli

7

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A Fontana

8

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F Andreoni

9

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A Falcone

10

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E Canestrari

11

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G Tonini

12

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D Mari

13

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P Lippe

14

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F Pizzagalli

15

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G Schiavon

16

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P Alessandroni

17

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L Giustini

18

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P Maltese

19

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E Testa

20

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E T Menichetti

21

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M Magnani

The Pharmacogenomics Journal

22

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language of work or name

English

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publication date

August 2008

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published in

1 reference

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

PubMed

volume

8

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issue

4

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page(s)

278-88

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cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500463

Topoisomerase I inhibitors: camptothecins and beyond

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Systemic therapy for metastatic colorectal cancer: current options, current evidence

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

21 January 2018

Cancer pharmacogenetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Pharmacogenetics of irinotecan toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Relationships between promoter polymorphisms in the thymidylate synthase gene and mRNA levels in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Methyl-group metabolism and the response of colorectal cancer to 5-fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: a molecular and clinical study of 75 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Induction of biphasic DNA double strand breaks and activation of multiple repair protein complexes by DNA topoisomerase I drug 7-ethyl-10-hydroxy-camptothecin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Molecular determinants of irinotecan efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Polymorphisms in DNA repair and environmental interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Single nucleotide polymorphism in the 5' tandem repeat sequences of thymidylate synthase gene predicts for response to fluorouracil-based chemotherapy in advanced colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Methylenetetrahydrofolate reductase gene polymorphisms: genomic predictors of clinical response to fluoropyrimidine-based chemotherapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Differential stability of thymidylate synthase 3'-untranslated region polymorphic variants regulated by AUF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

The Role of ABC Transporters in Clinical Practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Pharmacogenetics of uridine diphosphoglucuronosyltransferase (UGT) 1A family members and its role in patient response to irinotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Influence of DNA repair gene polymorphisms on the yield of chromosomal aberrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

XRCC3 is required for efficient repair of chromosome breaks by homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Tumor Thymidylate Synthase 1494del6 Genotype As a Prognostic Factor in Colorectal Cancer Patients Receiving Fluorouracil-Based Adjuvant Treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

Functional Analysis and DNA Polymorphism of the Tandemly Repeated Sequences in the 5'-terminal Regulatory Region of the Human Gene for Thymidylate Synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

7 January 2021

UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

7 January 2021

The Role of UGT1A1*28 Polymorphism in the Pharmacodynamics and Pharmacokinetics of Irinotecan in Patients With Metastatic Colorectal Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

7 January 2021

A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500463

7 January 2021