Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity (Q27934192)

PubMed

1 December 2016

title

Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity (English)

1 reference

PubMed

Translation initiation factor eIF5B YAL035W

1 December 2016

main subject

1 reference

GOA release 2020-03-11

6

Jon R Lorsch

0 references

Thomas Dever

7

object named as

Thomas E Dever

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Antonina Roll-Mecak

object named as

Antonina Roll-Mecak

3

0 references

Stephen K Burley

object named as

Stephen K Burley

5

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author name string

Byung-Sik Shin

1

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David Maag

2

0 references

M Shamsul Arefin

4

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language of work or name

English

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publication date

27 December 2002

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1 reference

Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation

1 December 2016

volume

111

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issue

7

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page(s)

1015-25

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cites work

1 reference

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Development and characterization of a reconstituted yeast translation initiation system.

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Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.

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A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo

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7 January 2021

Promotion of met-tRNAiMet binding to ribosomes by yIF2, a bacterial IF2 homolog in yeast

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7 January 2021

Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2

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7 January 2021

Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

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Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 A resolution

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Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron

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A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae

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GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae

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7 January 2021

Initiation of translation in prokaryotes and eukaryotes

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Late events in translation initiation. Adjustment of fMet-tRNA in the ribosomal P-site

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In vitro study of two dominant inhibitory GTPase mutants of Escherichia coli translation initiation factor IF2. Direct evidence that GTP hydrolysis is necessary for factor recycling

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GTPase activity of dynamin and resulting conformation change are essential for endocytosis

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Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system

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Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast

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Binding of Escherichia coli initiation factor IF2 to 30S ribosomal subunits: a functional role for the N-terminus of the factor

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Conformationally Restricted Elongation Factor G Retains GTPase Activity but Is Inactive in Translocation on the Ribosome

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The joining of ribosomal subunits in eukaryotes requires eIF5B.

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Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

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X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding

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7 January 2021

Engaging the ribosome: universal IFs of translation.

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Comparative protein modelling by satisfaction of spatial restraints

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Database of homology-derived protein structures and the structural meaning of sequence alignment

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Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis

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Dynamic properties of the Ras switch I region and its importance for binding to effectors

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G protein mechanisms: insights from structural analysis

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Visualization of elongation factor Tu on the Escherichia coli ribosome.

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Late events of translation initiation in bacteria: a kinetic analysis

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The guanine nucleotide-binding switch in three dimensions

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017