The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release (Q27933726)

PubMed

1 December 2016

title

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release (English)

1 reference

PubMed

proteasome-activating activity

1 December 2016

main subject

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0036402

Proteasome regulatory particle base subunit RPT2 YDL007W

1 reference

GOA release 2020-03-11

author name string

A Köhler

1

0 references

P Cascio

2

0 references

D S Leggett

3

0 references

K M Woo

4

0 references

A L Goldberg

5

0 references

D Finley

6

0 references

language of work or name

English

0 references

publication date

June 2001

0 references

1 reference

Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum

1 December 2016

volume

7

0 references

issue

6

0 references

page(s)

1143-52

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

The proteasome: paradigm of a self-compartmentalizing protease

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

1 reference

7 January 2021

The base of the proteasome regulatory particle exhibits chaperone-like activity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

The proteasome, a novel protease regulated by multiple mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Decelerated degradation of short peptides by the 20S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

The human 26 S and 20 S proteasomes generate overlapping but different sets of peptide fragments from a model protein substrate.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

The regulatory particle of the Saccharomyces cerevisiae proteasome.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

A role for the proteasome regulator PA28alpha in antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Structure of 20S proteasome from yeast at 2.4 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

A gated channel into the proteasome core particle

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

1 reference

7 January 2021

Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Structural features of the 26 S proteasome complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Opening doors into the proteasome.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

The proteasome activator 11 S REG (PA28) and class I antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Degradation of cell proteins and the generation of MHC class I-presented peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Structure and mechanism of ATP-dependent proteases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Evidence for the existence of a non-catalytic modifier site of peptide hydrolysis by the 20 S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Two new proteases in the MHC class I processing pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Recognition of the polyubiquitin proteolytic signal

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Global unfolding of a substrate protein by the Hsp100 chaperone ClpA.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Existence of a molecular ruler in proteasomes suggested by analysis of degradation products

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Structural basis for the activation of 20S proteasomes by 11S regulators

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X

7 January 2021

10.1016/S1097-2765(01)00274-X

Identifiers

DOI

0 references

1 reference

PubMed