On the multiple roles of the voltage gated sodium channel β1 subunit in genetic diseases (Q28080803)

Oscar Moran

series ordinal

2

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language of work or name

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18 May 2015

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Frontiers in Pharmacology

published in

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volume

6

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page(s)

108

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Crystal Structure and Molecular Imaging of the Nav Channel 3 Subunit Indicates a Trimeric Assembly

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Crystallographic insights into sodium-channel modulation by the β4 subunit

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Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans

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Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals

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Molecular cloning and functional expression of the human sodium channel β1B subunit, a novel splicing variant of the β1 subunit

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Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2

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beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics

20 March 2017

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Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R

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A deletion in SCN1B is associated with febrile seizures and early-onset absence epilepsy

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Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1

20 March 2017

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Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin

20 March 2017

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Modulation of sodium current in mammalian cells by an epilepsy-correlated beta 1-subunit mutation

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Contactin associates with Na+ channels and increases their functional expression

20 March 2017

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Sodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact

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Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel

20 March 2017

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Severe myoclonic epilepsy in infancy: clinical analysis and relation to SCN1A mutations in a Japanese cohort

20 March 2017

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Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin

20 March 2017

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Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture

20 March 2017

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Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif

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Differential gene expression profiles of two excitable rat cell lines after over-expression of WT- and C121W-β1 sodium channel subunits.

20 March 2017

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Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum

29 September 2017

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29 September 2017

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Enhanced in vitro CA1 network activity in a sodium channel β1(C121W) subunit model of genetic epilepsy.

29 September 2017

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Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression

29 September 2017

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Functional modulation of voltage-dependent sodium channel expression by wild type and mutated C121W-β1 subunit.

29 September 2017

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Nontruncating SCN1A mutations associated with severe myoclonic epilepsy of infancy impair cell surface expression

29 September 2017

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Different degrees of loss of function between GEFS+ and SMEI Nav 1.1 missense mutants at the same residue induced by rescuable folding defects

29 September 2017

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Voltage-gated sodium channels at 60: structure, function and pathophysiology

29 September 2017

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A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents

29 September 2017

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Na Channel β Subunits: Overachievers of the Ion Channel Family

29 September 2017

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Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy

29 September 2017

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New mutation c.374C>T and a putative disease-associated haplotype within SCN1B gene in Tunisian families with febrile seizures

29 September 2017

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Sodium channel SCN1A and epilepsy: mutations and mechanisms

29 September 2017

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Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus

29 September 2017

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Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth

29 September 2017

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A functional null mutation of SCN1B in a patient with Dravet syndrome

29 September 2017

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A rescuable folding defective Nav1.1 (SCN1A) sodium channel mutant causes GEFS+: common mechanism in Nav1.1 related epilepsies?

29 September 2017

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An emerging role for voltage-gated Na+ channels in cellular migration: regulation of central nervous system development and potentiation of invasive cancers

29 September 2017

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Generalized epilepsy with febrile seizures plus-associated sodium channel beta1 subunit mutations severely reduce beta subunit-mediated modulation of sodium channel function.

29 September 2017

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Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons

29 September 2017

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The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel function

29 September 2017

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Brugada syndrome: clinical, genetic, molecular, cellular and ionic aspects

29 September 2017

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Increased neuronal firing in computer simulations of sodium channel mutations that cause generalized epilepsy with febrile seizures plus

29 September 2017

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Sodium channel heterologous expression in mammalian cells and the role of the endogenous beta1-subunits

29 September 2017

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Generalized epilepsy with febrile seizures plus: mutation of the sodium channel subunit SCN1B.

29 September 2017

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29 September 2017

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29 September 2017

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Inactivation defects caused by myotonia-associated mutations in the sodium channel III-IV linker

29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes

21 January 2018

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Sodium current and potassium transient outward current genes in Brugada syndrome: screening and bioinformatics

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Na+ channel subunits and Ig domains

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The intracellular segment of the sodium channel beta 1 subunit is required for its efficient association with the channel alpha subunit

21 January 2018

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Skeletal muscle sodium channel is affected by an epileptogenic beta1 subunit mutation

21 January 2018

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A homozygous mutation of voltage-gated sodium channel β(I) gene SCN1B in a patient with Dravet syndrome

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Identifiers

DOI

10.3389/FPHAR.2015.00108

0 references

1 reference

PubMed publication ID

26042039

1 reference