Transformation of myeloid leukemia cells to cytokine independence by Bcr-Abl is suppressed by kinase-defective Hck (Q28138004)

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Acute leukaemia in bcr/abl transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Interleukin 3-dependent survival by the Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Autophosphorylation of the Fes tyrosine kinase. Evidence for an intermolecular mechanism involving two kinase domain tyrosine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Regulation of c-Fes tyrosine kinase and biological activities by N-terminal coiled-coil oligomerization domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Fibroblast transformation by Fps/Fes tyrosine kinases requires Ras, Rac, and Cdc42 and induces extracellular signal-regulated and c-Jun N-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Centrifugal enhancement of retroviral mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in Rat-2 fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Structures of Src-family tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Src family tyrosine kinases and growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000126200